Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease

ClinicalTrials.gov ID: NCT05650229

Public ClinicalTrials.gov record NCT05650229. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 20, 2026, 7:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Interventional, Randomised, Double-blind, Parallel-group, Placebo-controlled, Flexible-dose, Adaptive Study of the Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease

Study identification

NCT ID: NCT05650229
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Abliva AB; Industry
Enrollment: 180 participants

Conditions and interventions

Conditions

Primary Mitochondrial Disease

Interventions

KL1333 Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Dec 12, 2022
Primary completion: Sep 30, 2027
Completion: Oct 31, 2027
Last update posted: Apr 14, 2026

2022 – 2027

United States locations

U.S. sites: 11
U.S. states: 9
U.S. cities: 10

Facility	City	State	ZIP	Site status
University of California, Irvine - ALS & Neuromuscular Center	Orange	California	92868	Recruiting
The Regents of the University of California - San Diego	San Diego	California	292093	Recruiting
Children's Hospital Colorado - Center for Cancer and Blood Disorders (CCBD) - Anschutz Medical Campus Location	Aurora	Colorado	80045	Recruiting
Rare Disease Research, LLC	Atlanta	Georgia	303129	Recruiting
Mayo Clinic	Rochester	Minnesota	55905	Recruiting
Washington University School of Medicine - Center for Advanced Medicine (CAM) - Neuroscience Center	St Louis	Missouri	63110	Not yet recruiting
Columbia University Irving Medical Center	New York	New York	100032	Not yet recruiting
Akron Children's Hospital	Akron	Ohio	44307	Recruiting
UPMC Children's Hospital of Pittsburgh	Pittsburgh	Pennsylvania	15224	Not yet recruiting
Baylor College of Medicine (BCM)	Houston	Texas	77030	Recruiting
The University of Texas Health Science Center at Houston	Houston	Texas	77030	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05650229, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 14, 2026 · Synced May 20, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05650229 live on ClinicalTrials.gov.

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