Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia and Bipolar Disorder (SERENITY III)
Public ClinicalTrials.gov record NCT05658510. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy And Safety of BXCL501 Evaluated For At-Home Use In A Multisite Double-Blind Placebo-Controlled Trial For Agitation Associated With Schizophrenia And Bipolar Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
In this study, an investigational medication named BXCL501 is being tested for the treatment of episodes of agitation associated with bipolar I and bipolar II disorder, schizophrenia, schizoaffective and schizophreniform disorder. This study compares the study drug to a placebo.
Study identification
- NCT ID
- NCT05658510
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 452 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 21, 2022 (Actual)
- Primary completion
- Aug 15, 2025 (Actual)
- Completion
- Aug 15, 2025 (Actual)
- Last update posted
- Aug 7, 2026
2022 – 2025
United States locations
- U.S. sites
- 24
- U.S. states
- 10
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| BioXcel Clinical Research Site 113 | Bellflower | California | 90706 | — |
| BioXcel Clinical Research Site 128 | Cerritos | California | 90703 | — |
| BioXcel Clinical Research Site 110 | Culver City | California | 90230 | — |
| BioXcel Clinical Research Site 108 | Garden Grove | California | 92845 | — |
| BioXcel Clinical Research Site 117 | Lemon Grove | California | 91945 | — |
| BioXcel Clinical Research Site 121 | Los Angeles | California | 90015 | — |
| BioXcel Clinical Research Site 123 | Oceanside | California | 92056 | — |
| BioXcel Clinical Research Site 104 | Orange | California | 92868 | — |
| BioXcel Clinical Research Site 133 | Rancho Cucamonga | California | 91730 | — |
| BioXcel Clinical Research Site 114 | Riverside | California | 92506 | — |
| BioXcel Clinical Research Site 129 | Denver | Colorado | 80209 | — |
| BioXcel Clinical Research Site 131 | Miami | Florida | 33122 | — |
| BioXcel Clinical Research Site 124 | Miami | Florida | 33186 | — |
| BioXcel Clinical Research Site 130 | Elgin | Illinois | 60123 | — |
| BioXcel Clinical Research Site 103 | Gaithersburg | Maryland | 20877 | — |
| BioXcel Clinical Research Site 118 | Las Vegas | Nevada | 89102 | — |
| BioXcel Clinical Research Site 137 | Las Vegas | Nevada | 89119 | — |
| BioXcel Clinical Research Site 105 | Berlin | New Jersey | 08009 | — |
| BioXcel Clinical Research Site 122 | Beachwood | Ohio | 44122 | — |
| BioXcel Clinical Research Site 136 | Austin | Texas | 78754 | — |
| BioXcel Clinical Research Site 102 | DeSoto | Texas | 75115 | — |
| BioXcel Clinical Research Site 125 | Irving | Texas | 75062 | — |
| BioXcel Clinical Research Site 127 | Plano | Texas | 75093 | — |
| BioXcel Clinical Research Site 126 | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05658510, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 7, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05658510 live on ClinicalTrials.gov.