Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients

ClinicalTrials.gov ID: NCT05669833

Public ClinicalTrials.gov record NCT05669833. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 20, 2026, 10:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients: a Pragmatic Trial (EVOLUTION)

Study identification

NCT ID: NCT05669833
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: University of Pennsylvania; Other
Enrollment: 63 participants

Conditions and interventions

Conditions

Psoriatic Arthritis

Interventions

Golimumab Drug
Guselkumab Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 80 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jul 13, 2023
Primary completion: Sep 30, 2026
Completion: Sep 30, 2026
Last update posted: Oct 8, 2025

2023 – 2026

United States locations

U.S. sites: 14
U.S. states: 10
U.S. cities: 14

Facility	City	State	ZIP	Site status
Family Arthritis Center	Loxahatchee Groves	Florida	33470	Recruiting
Healing Rheumatology	Plant City	Florida	33563	Recruiting
Southwest Florida Rheumatology	Riverview	Florida	33569	Recruiting
Parris and Associates	Lilburn	Georgia	30047	Recruiting
University of Massachusetts Chan Medical School	Worcester	Massachusetts	01655	Recruiting
University of Nebraska Medical Center	Omaha	Nebraska	68198	Recruiting
New York University	New York	New York	10016	Recruiting
Cincy Arthritis	Blue Ash	Ohio	45242	Recruiting
Southern Ohio Rheumatology	Wheelersburg	Ohio	45694	Recruiting
Hospital at the University of Pennsylvania	Philadelphia	Pennsylvania	19104	Recruiting
Cumberland Rheumatology	Crossville	Tennessee	38555	Recruiting
Heritage Rheumatology and Arthritis Care	Colleyville	Texas	76034	Recruiting
Texas Arthritis Center	El Paso	Texas	79902	Recruiting
University of Utah	Salt Lake City	Utah	84132	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05669833, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Oct 8, 2025 · Synced May 20, 2026

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The complete protocol, eligibility criteria, and contact information for NCT05669833 live on ClinicalTrials.gov.

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