Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

ClinicalTrials.gov ID: NCT05677100

Public ClinicalTrials.gov record NCT05677100. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 20, 2026, 7:27 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

DRAIN-HF: Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

Study identification

NCT ID: NCT05677100
Recruitment status: Recruiting
Study type: Interventional
Phase: Not applicable
Lead sponsor: Procyrion; Industry
Enrollment: 320 participants

Conditions and interventions

Conditions

Interventions

Aortix System Device

Device

Eligibility (public fields only)

Age range: 21 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Aug 22, 2023
Primary completion: Dec 31, 2026
Completion: Jul 31, 2027
Last update posted: Apr 6, 2026

2023 – 2027

United States locations

U.S. sites: 47
U.S. states: 19
U.S. cities: 38

Facility	City	State	ZIP	Site status
Banner--University Medical Center Phoenix	Phoenix	Arizona	85006	Recruiting
Mayo Clinic - Arizona	Phoenix	Arizona	85054	Recruiting
HonorHealth Medical Center	Scottsdale	Arizona	85258	Terminated
John Muir Health	Concord	California	94520	Recruiting
Zuckerberg San Francisco General	San Francisco	California	94110	Recruiting
San Francisco Veterans Administration	San Francisco	California	94121	Recruiting
University of California San Francisco	San Francisco	California	94143	Recruiting
Ascension Sacred Heart	Pensacola	Florida	32504	Withdrawn
Tallahassee Research Institute	Tallahassee	Florida	32308	Active, not recruiting
University of South Florida	Tampa	Florida	33606	Recruiting
BayCare Medical/St. Joseph's Hospital	Tampa	Florida	33607	Recruiting
AdventHealth Tampa	Tampa	Florida	33613	Recruiting
Cleveland Clinic Florida	Weston	Florida	33331	Recruiting
Emory University Hospital	Atlanta	Georgia	30308	Recruiting
Piedmont Healthcare Inc.	Augusta	Georgia	30309	Recruiting
Wellstar Research Institue	Marietta	Georgia	30060	Active, not recruiting
University of Chicago	Chicago	Illinois	60637	Recruiting
Advocate IMMC	Chicago	Illinois	60657	Recruiting
Advocate Aurora - Good Samaritan	Downers Grove	Illinois	60515	Recruiting
Ascension via Christi Kansas	Wichita	Kansas	67226	Terminated
University of Michigan, Cardiovascular Medicine	Ann Arbor	Michigan	48109	Withdrawn
Henry Ford	Detroit	Michigan	48202	Recruiting
University of Mississippi Medical Center	Jackson	Mississippi	39216	Recruiting
Hackensack University Medical Center	Hackensack	New Jersey	07601	Recruiting
Jersey Shore University Medical Center	Neptune City	New Jersey	07753	Recruiting
New York Presbyterian - Brooklyn Methodist Hospital	Brooklyn	New York	11215	Recruiting
Mount Sinai Morningside	New York	New York	10025	Recruiting
Nyph/Cumc	New York	New York	10032	Recruiting
Northwell Health (Lenox Hill)	New York	New York	10075	Terminated
Nuvance Health	Poughkeepsie	New York	12601	Recruiting
Northwell Health (Staten Island)	Staten Island	New York	10305	Recruiting
Atrium Health Sanger Heart and Vascular Institute	Charlotte	North Carolina	28204	Recruiting
Duke University Medical Center	Durham	North Carolina	27710	Recruiting
Novant Health New Hanover Regional Medical Center	Wilmington	North Carolina	28401	Recruiting
The Ohio State University	Columbus	Ohio	43210	Recruiting
Oklahoma Cardiovascular Research Group	Oklahoma City	Oklahoma	73120	Recruiting
Oregon Health & Sciences University	Portland	Oregon	97239	Active, not recruiting
Jefferson Abington Hospital	Abington	Pennsylvania	19001	Recruiting
Penn Presbyterian Medical Center	Philadelphia	Pennsylvania	19104	Recruiting
Thomas Jefferson University Hospital	Philadelphia	Pennsylvania	19107	Recruiting
AnMed Health	Anderson	South Carolina	29621	Recruiting
Baylor Scott & White	Fort Worth	Texas	76104	Withdrawn
Texas Heart Institute	Houston	Texas	77030	Recruiting
Baylor Scott & White	Plano	Texas	75093	Withdrawn
Intermountain Health	Murray	Utah	84107	Withdrawn
University of Virginia	Charlottesville	Virginia	22908	Terminated
Virginia Commonwealth University	Richmond	Virginia	23219	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05677100, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 6, 2026 · Synced May 20, 2026

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The complete protocol, eligibility criteria, and contact information for NCT05677100 live on ClinicalTrials.gov.

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