A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A
Public ClinicalTrials.gov record NCT05685238. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Open-label, Long-term Safety and Efficacy Study of Mim8 in Participants With Haemophilia A With or Without Inhibitors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is looking at how Mim8 works in people with haemophilia A, who either have inhibitors or do not have inhibitors. Mim8 is a new medicine that will be used to avoid bleeding episodes. Mim8 works by replacing the function of the missing clotting factor VIII (FVIII). The study will last for up to 5.5 years. The duration of the study depends on when the participant enrolled in this study. The study will end if Mim8 is approved and marketed in participant's country during the study, or the study will end in June 2028, whichever comes first. Participants will get up to 262 injections; the number of injections depends on how often participants will get injections and how long time participants take part in the study. While taking part in this study, there are some restrictions about what medicine participants can use. The study doctor will tell the participants more about this. In case the participants experience bleeds, these can be treated with additional haemostatic medicine as agreed with the study doctor. Female participants cannot take part if they are pregnant, breast-feeding or plan to get pregnant during the study period.
Study identification
- NCT ID
- NCT05685238
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 451 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 13, 2023 (Actual)
- Primary completion
- Jun 30, 2028 (Estimated)
- Completion
- Jun 30, 2028 (Estimated)
- Last update posted
- Sep 9, 2026
2023 – 2028
United States locations
- U.S. sites
- 15
- U.S. states
- 11
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's Hospital Los Angeles - Endocrinology | Los Angeles | California | 90027 | — |
| UC Denver Hemoph & Thrombo Ctr | Aurora | Colorado | 80045 | — |
| Univ of Miami/SCCC | Miami | Florida | 33136 | — |
| St Joseph's Hospital Foundation | Tampa | Florida | 33607 | — |
| Children's Healthcare Atlanta | Atlanta | Georgia | 30329 | — |
| Rush University Med. Cntr | Chicago | Illinois | 60612 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Indiana Hemophilia-Thromb Ctr | Indianapolis | Indiana | 46260 | — |
| University of Iowa_Iowa City | Iowa City | Iowa | 52242 | — |
| Central Michigan University | Detroit | Michigan | 48201 | — |
| Univ Hosp Cleveland Med Ctr | Cleveland | Ohio | 44106 | — |
| Dayton Children Hemostati Ctr | Dayton | Ohio | 45404 | — |
| Penn State MS Hershey Med Ctr | Hershey | Pennsylvania | 17033-2360 | — |
| St Christopher Hosp for Child | Philadelphia | Pennsylvania | 19134 | — |
| Vanderbilt U Med Ctr_Nashville | Nashville | Tennessee | 37212 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 126 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05685238, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 9, 2026 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05685238 live on ClinicalTrials.gov.