ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System
Public ClinicalTrials.gov record NCT05686317. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Sham-controlled Clinical Trial for Evaluation of the Edwards APTURE Transcatheter Shunt System (ALT-FLOW II)
Study identification
- NCT ID
- NCT05686317
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Lead sponsor
- Edwards Lifesciences
- Industry
- Enrollment
- 100 participants
Conditions and interventions
Conditions
Interventions
- Edwards APTURE transcatheter shunt system Device
- Sham procedure Diagnostic Test
Device · Diagnostic Test
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2023
- Primary completion
- Oct 31, 2026
- Completion
- Aug 30, 2030
- Last update posted
- Mar 12, 2026
2023 – 2030
United States locations
- U.S. sites
- 18
- U.S. states
- 11
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California Irvine | Irvine | California | 92868 | — |
| University of California San Diego | La Jolla | California | 92027 | — |
| Scripps Health | La Jolla | California | 92037 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| Ascension Illinois Heart and Vascular Medical Group | Elk Grove | Illinois | 60007 | — |
| Kansas University Medical Center | Kansas City | Kansas | 66160 | — |
| Abbott Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Mayo Clinic | Rochester | Minnesota | 55902 | — |
| St. Francis Hospital & Heart Center | Roslyn | New York | 11576 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Oklahoma Heart Institute | Tulsa | Oklahoma | 74104 | — |
| Oregon Health and Science University | Oregon City | Oregon | 97239 | — |
| Lankenau Medical Center | Wynnewood | Pennsylvania | 19096 | — |
| Medical University of South Carolina Charleston | Charleston | South Carolina | 29425' | — |
| HCA Houston Healthcare Medical Center | Houston | Texas | 77004 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05686317, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 12, 2026 · Synced Apr 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05686317 live on ClinicalTrials.gov.