AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants With Duchenne Muscular Dystrophy (DMD)
Public ClinicalTrials.gov record NCT05693142. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2/3 Open-label Study to Evaluate the Safety, Tolerability, Efficacy, Pharmacodynamics, and Pharmacokinetics of Intravenous RGX-202 Gene Therapy in Males With Duchenne Muscular Dystrophy (DMD)
Study identification
- NCT ID
- NCT05693142
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- REGENXBIO Inc.
- Industry
- Enrollment
- 65 participants
Conditions and interventions
Conditions
Interventions
- RGX-202 Genetic
Genetic
Eligibility (public fields only)
- Age range
- 1 Year and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 3, 2023
- Primary completion
- Jan 31, 2026
- Completion
- Jul 31, 2028
- Last update posted
- Dec 16, 2025
2023 – 2028
United States locations
- U.S. sites
- 13
- U.S. states
- 12
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202 | Recruiting |
| Stanford School of Medicine /Division of Neuromuscular Medicine | Palo Alto | California | 94304 | Recruiting |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | Recruiting |
| University of Florida | Gainesville | Florida | 32610 | Recruiting |
| Rare Disease Research | Atlanta | Georgia | 30329 | Recruiting |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611 | Recruiting |
| University of Iowa | Iowa City | Iowa | 52242 | Recruiting |
| University of Massachusetts Chan Medical School | Worcester | Massachusetts | 01608 | Recruiting |
| Cincinnati Children's | Cincinnati | Ohio | 45229 | Recruiting |
| Oregon Health & Science University | Portland | Oregon | 97239 | Recruiting |
| The University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | Recruiting |
| Children's Hospital of the King's Daughters | Norfolk | Virginia | 23510 | Recruiting |
| Children's Hospital of Richmond at Virginia Commonwealth University | Richmond | Virginia | 23298 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05693142, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 16, 2025 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05693142 live on ClinicalTrials.gov.