Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease

ClinicalTrials.gov ID: NCT05701358

Public ClinicalTrials.gov record NCT05701358. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 19, 2026, 11:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Trial of Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization Strategies & an Observational Study of Optical Coherence Tomography in Patients With Acute MI & Multivessel Coronary Artery Disease

Study identification

NCT ID: NCT05701358
Recruitment status: Recruiting
Study type: Interventional
Phase: Not applicable
Lead sponsor: Population Health Research Institute; Other
Enrollment: 5,100 participants

Conditions and interventions

Conditions

Interventions

Angiography-guided NCL PCI Procedure
Physiology-guided NCL PCI Procedure

Procedure

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 21, 2023
Primary completion: May 31, 2028
Completion: May 31, 2028
Last update posted: Jun 18, 2025

2023 – 2028

United States locations

U.S. sites: 13
U.S. states: 9
U.S. cities: 12

Facility	City	State	ZIP	Site status
UCLA	Los Angeles	California	90095	Recruiting
University of California, San Francisco	San Francisco	California	94143	Recruiting
Cardiovascular Research Institute of Kansas	Wichita	Kansas	67226	Recruiting
The Johns Hopkins University School of Medicine	Baltimore	Maryland	21205	Recruiting
University of Michigan	Ann Arbor	Michigan	48109	Recruiting
Metropolitan Cardiology Consultants / Metropolitan Heart and Vascular Institute (MCC/MHVI)	Coon Rapids	Minnesota	55433	Recruiting
RWJ Barnabas Health	Jersey City	New Jersey	07302	Recruiting
Bassett Medical Center	Cooperstown	New York	13326	Recruiting
VA New York Harbor HealthCare System	New York	New York	10010	Recruiting
NYU Grossman School of Medicine	New York	New York	10016	Recruiting
Montefiore Medical Center	The Bronx	New York	10467	Recruiting
Cleveland Clinic	Cleveland	Ohio	44195	Recruiting
University of Virginia Medical Center	Charlottesville	Virginia	22903	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 100 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05701358, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jun 18, 2025 · Synced May 19, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05701358 live on ClinicalTrials.gov.

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