A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1468 in Healthy Adults ≥50 Years of Age
Public ClinicalTrials.gov record NCT05701800. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2, Randomized, Observer-Blind, Active-Controlled, Dose-Ranging Study to Evaluate the Safety, Reactogenicity and Immunogenicity of mRNA-1468, a Candidate Vaccine to Prevent Herpes Zoster (HZ) in Healthy Adults ≥50 Years of Age
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this first-in-human study is to evaluate the safety and immunogenicity of mRNA-1468.
Study identification
- NCT ID
- NCT05701800
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 659 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 23, 2023 (Actual)
- Primary completion
- Dec 31, 2025 (Actual)
- Completion
- Dec 31, 2025 (Actual)
- Last update posted
- Aug 5, 2026
2023 – 2025
United States locations
- U.S. sites
- 19
- U.S. states
- 12
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Velocity Clinical Research - Westlake | Los Angeles | California | 90057 | — |
| Tekton Research, Inc - Longmont Center | Longmont | Colorado | 80501 | — |
| Meridien Research | Lakeland | Florida | 33805 | — |
| Clinical Trials of Florida, LLC | Miami | Florida | 33186 | — |
| Floridian Clinical Research | Miami Lakes | Florida | 33016 | — |
| Florida Pulmonary Research Institute, LLC | Winter Park | Florida | 32789 | — |
| Centricity Research | Columbus | Georgia | 31904 | — |
| Great Lakes | Chicago | Illinois | 60640 | — |
| DM Clinical Research- River Forest | River Forest | Illinois | 60305 | — |
| Meridian Clinical Research - Dakota Dunes | Sioux City | Iowa | 51106 | — |
| Johnson County Clin-Trials (JCCT) | Lenexa | Kansas | 66219 | — |
| NOLA Research Works | New Orleans | Louisiana | 70115 | — |
| Velocity Clinical Research - Medford | Medford | Oregon | 97504 | — |
| DM Clinical Research - Philadelphia | Philadelphia | Pennsylvania | 19107 | — |
| WR-ClinSearch, LLC | Chattanooga | Tennessee | 37421 | — |
| Tekton Research | Austin | Texas | 78745 | — |
| Gadolin Research | Beaumont | Texas | 77702 | — |
| LinQ Research, LLC | Houston | Texas | 77087 | — |
| DM Clinical Research | Tomball | Texas | 77375 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05701800, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 5, 2026 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05701800 live on ClinicalTrials.gov.