A Study to Learn About a Modified RNA Vaccine Against Shingles in Healthy Adults
Public ClinicalTrials.gov record NCT05703607. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 1/2 RANDOMIZED, OBSERVER-BLIND STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF A MODIFIED RNA VACCINE AGAINST VARICELLA ZOSTER VIRUS IN HEALTHY INDIVIDUALS
Study identification
- NCT ID
- NCT05703607
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 484 participants
Conditions and interventions
Conditions
Interventions
- Candidate 1: PF-07915234: VZV modRNA Powder for Suspension for Injection Biological
- Candidate 1: PF-07915234: VZV modRNA Suspension for Injection Biological
- Candidate 2: PF-07921188: VZV modRNA Powder for Suspension for Injection Biological
- Candidate 2: PF-07921188: VZV modRNA Suspension for Injection Biological
- Candidate 3: PF-07921186: VZV modRNA Suspension for Injection Biological
- Shingrix Biological
Biological
Eligibility (public fields only)
- Age range
- 50 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 24, 2023
- Primary completion
- Sep 22, 2025
- Completion
- Sep 22, 2025
- Last update posted
- May 3, 2026
2023 – 2025
United States locations
- U.S. sites
- 35
- U.S. states
- 18
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Tri-City Cardiology | Gilbert | Arizona | 85233 | — |
| Aventiv Research Inc. | Mesa | Arizona | 85206 | — |
| Stanford University Medical Center | Palo Alto | California | 94304 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| GW Medical Faculty Associates | Washington D.C. | District of Columbia | 20037 | — |
| GW Vaccine Research Unit | Washington D.C. | District of Columbia | 20037 | — |
| Proactive Clinical Research,LLC | Fort Lauderdale | Florida | 33308 | — |
| Acevedo Clinical Research Associates | Miami | Florida | 33142 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| West Valley Cardiology Services | Meridian | Idaho | 83642 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Johnson County Clinical Trials | Lenexa | Kansas | 66219 | — |
| Centennial Medical Group | Columbia | Maryland | 21045 | — |
| Associates in Cardiology, PA | Silver Spring | Maryland | 20910 | — |
| C.S. Mott Clinical Research Center (CRC) | Detroit | Michigan | 48201 | — |
| Henry Ford St. John Hospital | Grosse Pointe Woods | Michigan | 48236 | — |
| Velocity Clinical Research, Norfolk | Norfolk | Nebraska | 68701 | — |
| Quality Clinical Research | Omaha | Nebraska | 68114 | — |
| University of Nevada School of Medicine - Reno | Reno | Nevada | 89557 | — |
| South Jersey Infectious Disease | Somers Point | New Jersey | 08244 | — |
| IMA Clinical Research | Albuquerque | New Mexico | 87109 | — |
| NYU Langone Health | New York | New York | 10016 | — |
| Tisch Hospital | New York | New York | 10016 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Rochester Clinical Research, LLC | Rochester | New York | 14609 | — |
| Accellacare - Wilmington | Wilmington | North Carolina | 28401 | — |
| Wilmington Health, PLLC (Cardiologist) | Wilmington | North Carolina | 28401 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Centricity Research Columbus Ohio Multispecialty | Columbus | Ohio | 43213 | — |
| Columbus Cardiovascular Associates, Inc. | Columbus | Ohio | 43213 | — |
| Clinical Trials of Texas, LLC dba Flourish Research | San Antonio | Texas | 78229 | — |
| Clinical Trials of Texas, LLC | San Antonio | Texas | 78229 | — |
| IMA Clinical Research San Antonio | San Antonio | Texas | 78229 | — |
| Dynamed Clinical Research, LP d/b/a DM Clinical Research | Tomball | Texas | 77375 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05703607, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2026 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05703607 live on ClinicalTrials.gov.