ClinicalTrials.gov record
Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD
ClinicalTrials.gov ID: NCT05711940
Public ClinicalTrials.gov record NCT05711940. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 5, 2026, 3:47 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With Treatment-resistant Depression
Study identification
- NCT ID
- NCT05711940
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- COMPASS Pathways
- Industry
- Enrollment
- 572 participants
Conditions and interventions
Conditions
Interventions
- Psilocybin Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 13, 2023
- Primary completion
- Jan 31, 2026
- Completion
- Nov 30, 2026
- Last update posted
- Jan 11, 2026
2023 – 2026
United States locations
- U.S. sites
- 62
- U.S. states
- 17
- U.S. cities
- 53
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Lighthouse Psychiatry Scottsdale | Gilbert | Arizona | 85234 | — |
| Clinical Innovations, Inc. | Bellflower | California | 90706 | — |
| M3 Wake Research | Encino | California | 91316 | — |
| The Regents of the University of California - San Diego | La Jolla | California | 92037-1337 | — |
| Kadima Neuropsychiatry Institute | La Jolla | California | 92037 | — |
| CalNeuro Research Group, Inc | Los Angeles | California | 90025 | — |
| Catalina Research Institute, LLC | Montclair | California | 91763 | — |
| Piedmont Hospital Neuroscience Centre | Oakland | California | 94610 | — |
| ATP Clinical Research, Inc. | Orange | California | 92868 | — |
| CITrials | Riverside | California | 92506 | — |
| Lumos Clinical Research Center | San Jose | California | 95124 | — |
| Syrentis Clinical Research | Santa Ana | California | 92705 | — |
| Stanford University | Stanford | California | 94305 | — |
| ASCLEPES Research Centers | Thousand Oaks | California | 93012 | — |
| Pacific Clinical Research Management Group, LLC | Upland | California | 91786 | — |
| Innovative Clinical Research, Inc. | Lauderhill | Florida | 33319 | — |
| Central Miami Medical Institute, LLC | Miami | Florida | 33125 | — |
| Behavioral Clinical Research, Inc. | Miami Lakes | Florida | 33016 | — |
| Health Synergy Clinical Research | Okeechobee | Florida | 34972 | — |
| Clinical Neurosciecne Solutions, Inc. dba CNS Healthcare | Orlando | Florida | 32801 | — |
| APG Research, LLC- Advanced Psychiatric Group | Orlando | Florida | 32803 | — |
| University South Florida | Tampa | Florida | 33613-4788 | — |
| Stedman Clinical Trials | Tampa | Florida | 33613 | — |
| Health Synergy Clinical Research, LLC | West Palm Beach | Florida | 33407 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| iResearch Atlanta | Decatur | Georgia | 30030 | — |
| Rush University Medical Center | Chicago | Illinois | 60612-3227 | — |
| Uptown Research Institute, LLC | Chicago | Illinois | 60640 | — |
| Psychiatric Medicine Associates | Skokie | Illinois | 60076 | — |
| Harvard Medical School - McLean Hospital | Belmont | Massachusetts | 02478-1064 | — |
| Adams Clinical - Boston (Copley Clinical) | Boston | Massachusetts | 02116 | — |
| University of Massachusetts Medical School | North Worcester | Massachusetts | 01655 | — |
| Adams Clinical - Boston | Watertown | Massachusetts | 02472 | — |
| Michigan Clinical Research Institute PC | Ann Arbor | Michigan | 48105 | — |
| University Of Michigan Comprehensive Depression Center | Ann Arbor | Michigan | 48109-2700 | — |
| Institute for Integrative Therapies | Eden Prairie | Minnesota | 55347 | — |
| St. Charles Psychiatric Associates - Midwest Research Group | Saint Charles | Missouri | 63304 | — |
| Alivation Research, LLC. | Lincoln | Nebraska | 68526 | — |
| Hassman Research Institute | Berlin | New Jersey | 08009 | — |
| Princeton Medical Institute | Princeton | New Jersey | 08540 | — |
| Bio Behavioral Health | Toms River | New Jersey | 08755 | — |
| Dent Neurosciences Research Center, Inc. | Amherst | New York | 14226-1727 | — |
| Fieve Clinical Research, Inc | New York | New York | 10017 | — |
| Spectrum Neuroscience and Treatment Institute | New York | New York | 10021-4157 | — |
| Adams Clinical - New York | New York | New York | 10029 | — |
| New York State Psychiatric Institute | New York | New York | 10032 | — |
| Richmond Behavioral Associates | Staten Island | New York | 10312 | — |
| Adams Clinical - New York | The Bronx | New York | 10461 | — |
| University of Cincinnati, Department of Psychiatry & Behavirol Neuroscience | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic - Lutheran Hospital | Cleveland | Ohio | 44113-3108 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Suburban Research Associates | Media | Pennsylvania | 19063 | — |
| The University of Texas at Austin - Dell Medical School | Austin | Texas | 78712 | — |
| Houston Clinical Trials, LLC | Bellaire | Texas | 77401 | — |
| Relaro Medical Trials | Dallas | Texas | 75243 | — |
| Center for Depression Research and Clinical Care | Dallas | Texas | 75247-9119 | — |
| North Texas Clinical Trials | Fort Worth | Texas | 76104 | — |
| Brain Health Consultants and TMS Center | Houston | Texas | 77046-2401 | — |
| HCA Healthcare Research Institute - Medical City Green Oaks Hospital | Plano | Texas | 75251 | — |
| Cedar Clinical Research | Draper | Utah | 84020 | — |
| The University of Utah - Huntsman Mental Health Institute | Salt Lake City | Utah | 84108 | — |
| Seattle Neuropsychiatric Treatment Center | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 54 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05711940, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 11, 2026 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05711940 live on ClinicalTrials.gov.