Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)

ClinicalTrials.gov ID: NCT05712694

Public ClinicalTrials.gov record NCT05712694. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 23, 2026, 3:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

ADI-PEG 20 or Placebo Plus Gemcitabine and Docetaxel in Previously Treated Subjects With Leiomyosarcoma (ARGSARC): A Randomized, Double Blind, Multi-Center Phase 3 Trial

Study identification

NCT ID: NCT05712694
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Polaris Group; Industry
Enrollment: 300 participants

Conditions and interventions

Conditions

Soft Tissue Sarcoma

Interventions

ADI PEG20 Drug
Placebo Other

Drug · Other

Eligibility (public fields only)

Age range: 18 Years to 99 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 28, 2023
Primary completion: Dec 29, 2027
Completion: Dec 29, 2027
Last update posted: Apr 19, 2026

2023 – 2027

United States locations

U.S. sites: 26
U.S. states: 17
U.S. cities: 24

Facility	City	State	ZIP	Site status
Mayo Clinic Arizona	Phoenix	Arizona	85054	Recruiting
USC Norris comprehensive cancer center	Los Angeles	California	90033	Recruiting
Stanford University Medical Centre	Palo Alto	California	94304	Recruiting
UCSF	San Francisco	California	94158	Recruiting
UCLA	Santa Monica	California	90404	Recruiting
University of Colorado Cancer Center/ CU Anschutz Medical Campus	Aurora	Colorado	80045	Recruiting
Mayo Clinic Florida	Jacksonville	Florida	32224	Recruiting
University of Miami/ Sylvester Comprehensive Cancer Center	Miami	Florida	33136	Recruiting
Moffitt Cancer Center	Tampa	Florida	33612	Recruiting
Northwestern	Chicago	Illinois	60611	Recruiting
Indiana University	Indianapolis	Indiana	46202	Recruiting
University of Iowa	Iowa City	Iowa	52242	Active, not recruiting
Mass General Brigham Cancer Center	Boston	Massachusetts	02114	Recruiting
University of Michigan	Ann Arbor	Michigan	48109	Recruiting
Mayo Clinic Rochester	Rochester	Minnesota	55905	Recruiting
Washington University School of Medicine - Siteman Cancer Center	St Louis	Missouri	63110	Recruiting
NYU Langone Health	New York	New York	10016	Recruiting
Columbia University	New York	New York	10032	Not yet recruiting
Memorial Sloan Kettering Cancer Center	New York	New York	10065	Recruiting
Duke Cancer Institute	Durham	North Carolina	27710	Recruiting
University Hospitals Cleveland Medical Center	Cleveland	Ohio	44106	Recruiting
Ohio State University Wexner Medical Center/ The James Cancer Hospital and Solove Research Institute	Columbus	Ohio	43210	Recruiting
UPenn (Abramson Cancer Center, Pennsylvania Hospital)	Philadelphia	Pennsylvania	19106	Recruiting
UPMC Hillman Cancer Center	Pittsburgh	Pennsylvania	15232	Recruiting
University of Texas MD Anderson Cancer Center	Houston	Texas	77030	Recruiting
Medical College of Wisconsin/ Froedtert Hospital	Milwaukee	Wisconsin	53226	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05712694, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 19, 2026 · Synced Apr 23, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05712694 live on ClinicalTrials.gov.

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