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Terminated Phase 2 Interventional

VTX958 Versus Placebo for the Treatment of Active Psoriatic Arthritis (Tranquility-PsA)

ClinicalTrials.gov ID: NCT05715125

Public ClinicalTrials.gov record NCT05715125. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of VTX958 in Patients With Active Psoriatic Arthritis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The objective of this study is to evaluate if VTX958 is safe and effective in adult participants with active Psoriatic Arthritis. Approximately 195 eligible participants will take VTX958 Dose A, VTX958 Dose B, or matching placebo (no active drug) for 16 weeks and then move on to a 36 week Long Term Extension (LTE). The study will include 16 weeks of treatment, 36 weeks of LTE, and a 30-day follow-up period.

Study identification

NCT ID
NCT05715125
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Ventyx Biosciences, Inc
Industry
Enrollment
205 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2023 (Actual)
Primary completion
Jan 2, 2024 (Actual)
Completion
Jan 2, 2024 (Actual)
Last update posted
Dec 27, 2024

2023 – 2024

United States locations

U.S. sites
15
U.S. states
10
U.S. cities
15
Facility City State ZIP Site status
Site # 840001 Phoenix Arizona 85032 —
Site # 840016 Newport Beach California 92663 —
Site # 840004 Clearwater Florida 33765 —
Site # 840014 Miami Lakes Florida 33014 —
Site # 840017 Lexington Kentucky 40504 —
Site # 840018 Okemos Michigan 48864 —
Site #840012 Saint Clair Shores Michigan 48081 —
Site # 840019 Eagan Minnesota 55121 —
Site # 840003 Middleburg Heights Ohio 44130 —
Site # 840007 Duncansville Pennsylvania 16635 —
Site # 840010 Baytown Texas 77521 —
Site # 840006 Lubbock Texas 79410 —
Site # 840015 Mesquite Texas 75150 —
Site # 840011 Beckley West Virginia 25802 —
Site # 840008 South Charleston West Virginia 25309 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05715125, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 27, 2024 · Synced Oct 29, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05715125 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →