An Open-label Study of XEN1101 in Epilepsy
Public ClinicalTrials.gov record NCT05718817. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Open-label, Long-term, Safety, Tolerability, and Efficacy Study of XEN1101 in Subjects Diagnosed With Epilepsy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the long term safety, tolerability, pharmacokinetics (PK), and efficacy of XEN1101 in subjects with Focal Onset Seizures (FOS) or Primary Generalized Tonic-Clonic Seizures (PGTCS) for the treatment of seizures for up to 6 years.
Study identification
- NCT ID
- NCT05718817
- Recruitment status
- Enrolling by invitation
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 880 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 25, 2023 (Actual)
- Primary completion
- Apr 2033 (Estimated)
- Completion
- Jun 2033 (Estimated)
- Last update posted
- Oct 8, 2026
2023 – 2033
United States locations
- U.S. sites
- 54
- U.S. states
- 28
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Xenoscience | Phoenix | Arizona | 85004 | — |
| University of Arizona - Health Sciences | Tucson | Arizona | 85724 | — |
| Clinical Trials, Inc | Little Rock | Arkansas | 72205 | — |
| Brain Science Research Institute | Los Angeles | California | 90025 | — |
| UC Irvine Health | Orange | California | 92868 | — |
| University of California, Davis Clinical & Translational Science Center Clinical Research (CCRC) | Sacramento | California | 95817 | — |
| University of Colorado Hospital Anschutz Outpatient Pavilion | Aurora | Colorado | 80045 | — |
| Mayo Clinic Florida | Jacksonville | Florida | 32224 | — |
| Serenity Research Center, LLC | Miami | Florida | 33176 | — |
| Research Institute of Orlando, LLC | Orlando | Florida | 32806 | — |
| Panhandle Research & Medical Clinic | Pensacola | Florida | 10021 | — |
| University of South Florida | Tampa | Florida | 33606 | — |
| Encore Medical Research of Weston, LLC | Weston | Florida | 33331 | — |
| Hawaii Pacific Neuroscience | Honolulu | Hawaii | 96817 | — |
| Consultants in Epilepsy and Neurology | Boise | Idaho | 83704 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| The University of Kansas Medical Center | Kansas City | Kansas | 66103 | — |
| Bluegrass Epilepsy Research, LLC | Lexington | Kentucky | 40504 | — |
| Kentucky Clinic | Lexington | Kentucky | 40536 | — |
| MMP Neurology | Scarborough | Maine | 04074 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Mid-Atlantic Epilepsy and Sleep Center | Bethesda | Maryland | 20817 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| UMass Chan Medical School | Worcester | Massachusetts | 06155 | — |
| University of Michigan Hospitals | Ann Arbor | Michigan | 48109-2435 | — |
| Wayne State University | Detroit | Michigan | 48201 | — |
| Michigan State University | East Lansing | Michigan | 48824 | — |
| Cornwell Health (Spectrum Health Hospitals) | Grand Rapids | Michigan | 49503 | — |
| Minneapolis Clinic of Neurology | Burnsville | Minnesota | 55337 | — |
| Saint Louis University Medical School | St Louis | Missouri | 63104 | — |
| Northeast Epilepsy Group | Hackensack | New Jersey | 07601 | — |
| Dent Neurosciences Research Center | Buffalo | New York | 14226 | — |
| New York University Comprehensive Epilepsy Center | New York | New York | 10016 | — |
| Mount Sinai Health | New York | New York | 10029 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Montefiiore Medical Center | The Bronx | New York | 10467 | — |
| Onsite Clinical Solutions | Charlotte | North Carolina | 28211 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| Meridian Clinical Research, LLC | Raleigh | North Carolina | 27607 | — |
| Summa Health | Akron | Ohio | 44304 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| The Ohio State University Brain and Spine Hospital | Columbus | Ohio | 43210 | — |
| Providence Neurological Specialities | Portland | Oregon | 97225 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Austin Epilepsy Care Center | Austin | Texas | 78758 | — |
| ANESC Research | El Paso | Texas | 79912 | — |
| UT Health San Antonio | San Antonio | Texas | 78229 | — |
| University of Utah Clinical Neurosciences Center | Salt Lake City | Utah | 84132 | — |
| Carilion Clinic | Roanoke | Virginia | 24013 | — |
| Sentara Neurology Specialists | Virginia Beach | Virginia | 23456 | — |
| University of Washington Main Hospital | Seattle | Washington | 10012 | — |
| Aurora St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 98 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05718817, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 8, 2026 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05718817 live on ClinicalTrials.gov.