A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission
Public ClinicalTrials.gov record NCT05719441. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Randomized, Placebo-Controlled Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission
Study identification
- NCT ID
- NCT05719441
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Enrollment
- 48 participants
Conditions and interventions
Conditions
Interventions
- ART Drug
- PGT121.414.LS Biological
- Placebo Other
- VRC07-523LS Biological
Drug · Biological · Other
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 18, 2024
- Primary completion
- Apr 5, 2028
- Completion
- Sep 5, 2028
- Last update posted
- Apr 20, 2026
2024 – 2028
United States locations
- U.S. sites
- 32
- U.S. states
- 18
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| 31788, Alabama CRS | Birmingham | Alabama | 35222 | Not yet recruiting |
| 1201, University of Southern California CRS | Los Angeles | California | 90033-1079 | Not yet recruiting |
| 601, University of California, Los Angeles CARE Center CRS | Los Angeles | California | 90035 | Not yet recruiting |
| 701, UCSD Antiviral Research Center CRS | San Diego | California | 92103 | Not yet recruiting |
| 801, University of California, San Francisco HIV/AIDS CRS | San Francisco | California | 94110 | Not yet recruiting |
| 603, Harbor University of California Los Angeles Center CRS | Torrance | California | 90502 | Not yet recruiting |
| 6101, University of Colorado Hospital CRS | Aurora | Colorado | 80045 | Recruiting |
| 31791, Whitman-Walker Institute, Inc. CRS | Washington D.C. | District of Columbia | 20005 | Not yet recruiting |
| 5802, The Ponce de Leon Center CRS | Atlanta | Georgia | 30308-2012 | Recruiting |
| 2701, Northwestern University CRS | Chicago | Illinois | 60611 | Not yet recruiting |
| 2702, Rush University CRS | Chicago | Illinois | 60612 | Not yet recruiting |
| 201, Johns Hopkins University CRS | Baltimore | Maryland | 21205 | Not yet recruiting |
| 101, Massachusetts General Hospital CRS (MGH CRS) | Boston | Massachusetts | 02114 | Not yet recruiting |
| 107, Brigham and Women's Hospital Therapeutics (BWH TCRS) CRS | Boston | Massachusetts | 02115 | Not yet recruiting |
| 2101, Washington University Therapeutics (WT) CRS | St Louis | Missouri | 63110-1010 | Not yet recruiting |
| 31786, New Jersey Medical School Clinical Research Center CRS | Newark | New Jersey | 07103 | Not yet recruiting |
| 7804, Weill Cornell Chelsea CRS | New York | New York | 10010 | Not yet recruiting |
| 30329, Columbia Physicians & Surgeons (P&S) CRS | New York | New York | 10032-3732 | Not yet recruiting |
| 7803, Weill Cornell Uptown CRS | New York | New York | 10065 | Not yet recruiting |
| 31787, University of Rochester Adult HIV Therapeutic Strategies Network CRS | Rochester | New York | 14642 | Not yet recruiting |
| 3201, Chapel Hill CRS | Chapel Hill | North Carolina | 27599-7215 | Not yet recruiting |
| 3203, Greensboro CRS | Greensboro | North Carolina | 27401 | Not yet recruiting |
| 2401, Cincinnati CRS | Cincinnati | Ohio | 45267-0405 | Not yet recruiting |
| 2501, Case CRS | Cleveland | Ohio | 44106 | Not yet recruiting |
| 2301, Ohio State University CRS | Columbus | Ohio | 43210-1282 | Recruiting |
| 6201, Penn Therapeutics CRS | Philadelphia | Pennsylvania | 19104 | Not yet recruiting |
| 1001, University of Pittsburgh CRS | Pittsburgh | Pennsylvania | 15213 | Not yet recruiting |
| 2951, The Miriam Hospital (TMH) CRS | Providence | Rhode Island | 02904 | Not yet recruiting |
| 3652, Vanderbilt Therapeutics (VT) CRS | Nashville | Tennessee | 37204 | Not yet recruiting |
| 31443, Trinity Health and Wellness Center CRS | Dallas | Texas | 75208 | Not yet recruiting |
| 31473, Houston AIDS Research Team CRS | Houston | Texas | 77030 | Recruiting |
| 1401, University of Washington Positive Research CRS | Seattle | Washington | 98104 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05719441, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 20, 2026 · Synced Apr 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05719441 live on ClinicalTrials.gov.