ClinicalTrials.gov record
Active, not recruiting Phase 2 Interventional

Testing the Effectiveness of an Anti-cancer Drug, Triapine, When Used With Targeted Radiation-based Treatment (Lutetium Lu 177 Dotatate), Compared to Lutetium Lu 177 Dotatate Alone for Metastatic Neuroendocrine Tumors

ClinicalTrials.gov ID: NCT05724108

Public ClinicalTrials.gov record NCT05724108. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 6:34 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Randomized Control Trial of Triapine Plus Lutetium Lu 177 Dotatate Versus Lutetium Lu 177 Dotatate Alone for Well-Differentiated Somatostatin Receptor-Positive Neuroendocrine Tumors

Study identification

NCT ID
NCT05724108
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
National Cancer Institute (NCI)
NIH
Enrollment
94 participants

Conditions and interventions

Interventions

  • Biospecimen Collection Procedure
  • Computed Tomography Procedure
  • Lutetium Lu 177 Dotatate Drug
  • Magnetic Resonance Imaging Procedure
  • Triapine Drug

Procedure · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 29, 2023
Primary completion
Dec 8, 2026
Completion
Dec 8, 2026
Last update posted
Apr 12, 2026

2023 – 2026

United States locations

U.S. sites
25
U.S. states
11
U.S. cities
22
Facility City State ZIP Site status
City of Hope Comprehensive Cancer Center Duarte California 91010
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine California 92612
UC Irvine Health/Chao Family Comprehensive Cancer Center Orange California 92868
University of California Davis Comprehensive Cancer Center Sacramento California 95817
UM Sylvester Comprehensive Cancer Center at Aventura Aventura Florida 33180
UM Sylvester Comprehensive Cancer Center at Coral Gables Coral Gables Florida 33146
UM Sylvester Comprehensive Cancer Center at Deerfield Beach Deerfield Beach Florida 33442
UF Health Cancer Institute - Gainesville Gainesville Florida 32610
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami Florida 33136
UM Sylvester Comprehensive Cancer Center at Kendall Miami Florida 33176
UM Sylvester Comprehensive Cancer Center at Plantation Plantation Florida 33324
Northwestern University Chicago Illinois 60611
University of Kentucky/Markey Cancer Center Lexington Kentucky 40536
Rutgers Cancer Institute of New Jersey New Brunswick New Jersey 08903
NYP/Weill Cornell Medical Center New York New York 10065
Ohio State University Comprehensive Cancer Center Columbus Ohio 43210
University of Pittsburgh Cancer Institute (UPCI) Pittsburgh Pennsylvania 15232
MD Anderson in The Woodlands Conroe Texas 77384
M D Anderson Cancer Center Houston Texas 77030
MD Anderson West Houston Houston Texas 77079
MD Anderson League City League City Texas 77573
MD Anderson in Sugar Land Sugar Land Texas 77478
Huntsman Cancer Institute/University of Utah Salt Lake City Utah 84112
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center Madison Wisconsin 53718
University of Wisconsin Carbone Cancer Center - University Hospital Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05724108, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 12, 2026 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05724108 live on ClinicalTrials.gov.

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