Trial to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With PCED
Public ClinicalTrials.gov record NCT05727878. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Study to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With Persistent Corneal Epithelial Defect (PCED)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of the study is to investigate the safety and efficacy of KPI-012 compared to vehicle in participants who have a documented clinical diagnosis of PCED.
Study identification
- NCT ID
- NCT05727878
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 103 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 7, 2023 (Actual)
- Primary completion
- Sep 29, 2025 (Actual)
- Completion
- Oct 19, 2025 (Actual)
- Last update posted
- Oct 22, 2025
2023 – 2025
United States locations
- U.S. sites
- 43
- U.S. states
- 21
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Principal Investigator | Dothan | Alabama | 36301 | — |
| Principal Investigator | Irvine | California | 92897 | — |
| Principal Investigator | La Jolla | California | 92037 | — |
| Principal Investigator | Loma Linda | California | 92354 | — |
| Principal Investigator | Los Angeles | California | 90013 | — |
| Principal Investigator | Los Angeles | California | 90095 | — |
| Principal Investigator | Pasadena | California | 91107 | — |
| Principal Investigator | Rancho Cordova | California | 95670 | — |
| Principal Investigator | Aurora | Colorado | 80045 | — |
| Principal Investigator | Fort Collins | Colorado | 80528 | — |
| Principal Investigator | Littleton | Colorado | 80120 | — |
| Principal Investigator | Miami | Florida | 33136 | — |
| Principal Investigator | Miami | Florida | 33143 | — |
| Principal Investigator | Orange City | Florida | 32763 | — |
| Principal Investigator | Atlanta | Georgia | 30339 | — |
| Principal Investigator | Carmel | Indiana | 46290 | — |
| Principal Investigator | Indianapolis | Indiana | 46260 | — |
| Principal Investigator | Louisville | Kentucky | 40206 | — |
| Principal Investigator | Boston | Massachusetts | 02111 | — |
| Principal Investigator | Boston | Massachusetts | 02114 | — |
| Principal Investigator | Chesterfield | Missouri | 63017 | — |
| Principal Investigator | Kansas City | Missouri | 64111 | — |
| Principal Investigator | Kansas City | Missouri | 64133 | — |
| Principal Investigator | St Louis | Missouri | 63131 | — |
| Principal Investigator | Palisades Park | New Jersey | 07650 | — |
| Principal Investigator | New York | New York | 10036 | — |
| Principal Investigator | Rockville Centre | New York | 11570 | — |
| Principal investigator | Durham | North Carolina | 27710 | — |
| Principal Investigator | Garner | North Carolina | 27529 | — |
| Principal Investigator | Powell | Ohio | 43065 | — |
| Principal Investigator | Philadelphia | Pennsylvania | 19107 | — |
| Principal Investigator | Pittsburgh | Pennsylvania | 15219 | — |
| Principal Investigator | Rapid City | South Dakota | 57701 | — |
| Principal Investigator | Memphis | Tennessee | 38119 | — |
| Principal Investigator | Nashville | Tennessee | 37215 | — |
| Principal Investigator | Austin | Texas | 78712 | — |
| Principal Investigator | Austin | Texas | 78731 | — |
| Principal Investigator | Houston | Texas | 77030 | — |
| Principal Investigator | San Antonio | Texas | 78212 | — |
| Principal Investigator | Norfolk | Virginia | 23502 | — |
| Principal Investigator | Seattle | Washington | 98119 | — |
| Principal Investigator | Morgantown | West Virginia | 25606 | — |
| Principal Investigator | Kenosha | Wisconsin | 53142 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05727878, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 22, 2025 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05727878 live on ClinicalTrials.gov.