A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)
Public ClinicalTrials.gov record NCT05736419. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Pre-Transplant Immune Suppression With Hematopoietic Cell Transplantation From Haploidentical Donors for Adults and Children With Sickle Cell Disease or ß-Thalassemia (Haplo PTCy)
Study identification
- NCT ID
- NCT05736419
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Other
- Enrollment
- 24 participants
Conditions and interventions
Conditions
Interventions
- Bortezomib Drug
- Cyclophosphamide Drug
- Dexamethasone Drug
- Fludarabine Drug
- Mycophenolate Mofetil Drug
- Rabbit ATG Biological
- Rituximab Drug
- Tacrolimus Drug
Drug · Biological
Eligibility (public fields only)
- Age range
- 2 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 8, 2023
- Primary completion
- Feb 8, 2027
- Completion
- Feb 8, 2027
- Last update posted
- Apr 7, 2026
2023 – 2027
United States locations
- U.S. sites
- 6
- U.S. states
- 2
- U.S. cities
- 6
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Memorial Sloan Kettering at Basking Ridge (Consent only) | Basking Ridge | New Jersey | 07920 | Recruiting |
| Memorial Sloan Kettering Monmouth (Consent only) | Middletown | New Jersey | 07748 | Recruiting |
| Memorial Sloan Kettering Bergen (Consent only) | Montvale | New Jersey | 07645 | Recruiting |
| Memorial Sloan Kettering Suffolk - Commack (Consent only) | Commack | New York | 11725 | Recruiting |
| Memorial Sloan Kettering Westchester (Consent only) | Harrison | New York | 10604 | Recruiting |
| Memorial Sloan Kettering Nassau (All protocol activities) | Rockville Centre | New York | 11553 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05736419, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 7, 2026 · Synced May 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05736419 live on ClinicalTrials.gov.