ClinicalTrials.gov record
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Phase 2 Randomized Multisite Trial to Inform Public Health Strategies Involving the Use of MVA-BN Vaccine for Mpox

ClinicalTrials.gov ID: NCT05740982

Public ClinicalTrials.gov record NCT05740982. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 19, 2026, 8:01 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Randomized, Open-Label, Multisite Trial to Inform Public Health Strategies Involving the Use of MVA-BN Vaccine for Mpox

Study identification

NCT ID
NCT05740982
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Enrollment
450 participants

Conditions and interventions

Conditions

Interventions

  • JYNNEOS Biological

Biological

Eligibility (public fields only)

Age range
12 Years to 50 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 21, 2023
Primary completion
Aug 27, 2024
Completion
Aug 27, 2024
Last update posted
Mar 26, 2026

2023 – 2024

United States locations

U.S. sites
17
U.S. states
13
U.S. cities
16
Facility City State ZIP Site status
Children's of Alabama Child Health Research Unit (CHRU) Birmingham Alabama 35233-0011
George Washington University Medical Faculty Associates Washington D.C. District of Columbia 20037
Emory University School of Medicine Atlanta Georgia 30322-1014
University of Maryland, School of Medicine, Center for Vaccine Development and Global Health Baltimore Maryland 21201-1509
NIH Clinical Research Center, Investigational Drug Management and Research Section Bethesda Maryland 20892-1504
Brigham and Women's Hospital Boston Massachusetts 02115-6110
Saint Louis University Center for Vaccine Development St Louis Missouri 63104-1015
Washington University in St. Louis St Louis Missouri 63110-1010
University of Rochester Medical Center Rochester New York 14642-0001
Duke Vaccine and Trials Unit Durham North Carolina 27703
Cincinnati Children's Hospital Medical Center Vaccine Research Center Cincinnati Ohio 45229-3039
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19146
UPMC University Center Pittsburgh Pennsylvania 15213
Vanderbilt University Medical Center Nashville Tennessee 37212
University of Texas Medical Branch Galveston Texas 77555-0435
Baylor College of Medicine Houston Texas 77030-3411
Kaiser Permanente Washington Health Research Institute Seattle Washington 98101-1466

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05740982, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 26, 2026 · Synced May 19, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05740982 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →