An Open-label Study of Povetacicept in Participants With Autoimmune Cytopenias
Public ClinicalTrials.gov record NCT05757570. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Open-Label Study to Assess the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Povetacicept in Subjects With Autoimmune Cytopenias (RUBY-4)
Study identification
- NCT ID
- NCT05757570
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Alpine Immune Sciences, Inc.
- Industry
- Enrollment
- 30 participants
Conditions and interventions
Conditions
Interventions
- povetacicept Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2, 2023
- Primary completion
- Jun 30, 2026
- Completion
- Jun 30, 2026
- Last update posted
- Jul 3, 2025
2023 – 2026
United States locations
- U.S. sites
- 15
- U.S. states
- 8
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigational Site (230) | Los Angeles | California | 90033 | — |
| Investigational Site (401) | Washington D.C. | District of Columbia | 20007 | — |
| Investigational Site (419) | Cooper City | Florida | 33024 | — |
| Investigational Site (425) | Miami | Florida | 33143 | — |
| Investigational Site (219) | Iowa City | Iowa | 52242 | — |
| Investigational Site (435) | Columbia | Maryland | 21044 | — |
| Investigational site (405) | Lake Success | New York | 11042 | — |
| Investigational Site (423) | New Hyde Park | New York | 11040 | — |
| Investigational Site (421) | New York | New York | 10028 | — |
| Investigational Site (404) | New York | New York | 10065 | — |
| Investigational Site (420) | Shirley | New York | 11967 | — |
| Investigational Site (422) | The Bronx | New York | 10469 | — |
| Investigational Site (414) | Charlotte | North Carolina | 28204 | — |
| Investigational Site (402) | Greenville | North Carolina | 27834 | — |
| Investigational Site (411) | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05757570, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 3, 2025 · Synced May 16, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05757570 live on ClinicalTrials.gov.