A Study of CDX-0159 in Patients With Eosinophilic Esophagitis
Public ClinicalTrials.gov record NCT05774184. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Barzolvolimab (CDX-0159) in Adults With Active Eosinophilic Esophagitis (The "EvolvE" Study)
Study identification
- NCT ID
- NCT05774184
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Celldex Therapeutics
- Industry
- Enrollment
- 86 participants
Conditions and interventions
Conditions
Interventions
- Matching Placebo Drug
- barzolvolimab Biological
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2023
- Primary completion
- Jun 3, 2025
- Completion
- Jan 22, 2026
- Last update posted
- Apr 30, 2026
2023 – 2026
United States locations
- U.S. sites
- 24
- U.S. states
- 17
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AllerVie Clinical Research | Birmingham | Alabama | 35209 | — |
| One of a Kind Clinical Research Center | Scottsdale | Arizona | 85258 | — |
| GI Alliance- Arizona Digestive Health- Sun City | Sun City | Arizona | 85351 | — |
| Del Sol Research Management, LLC | Tucson | Arizona | 85715 | — |
| GW Research Inc. | Chula Vista | California | 91910 | — |
| Connecticut Clinical Research Institute, LLC | Bristol | Connecticut | 06416 | — |
| ENCORE Borland Groover Clinical Research | Jacksonville | Florida | 32256 | — |
| Gastroenterology of Greater Orlando | Orange City | Florida | 32763 | — |
| Treasure Valley Medical Research | Boise | Idaho | 83706 | — |
| Northwestern University | Chicago | Illinois | 60208 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center (KUMC) | Kansas City | Kansas | 66160 | — |
| Tandem Clinical Research | Marrero | Louisiana | 70072 | — |
| Boston Specialists - Boston Food Allergy Center | Boston | Massachusetts | 02111 | — |
| NYU Langone Health | New York | New York | 10016 | — |
| University of North Carolina (UNC) Hospitals | Chapel Hill | North Carolina | 27514 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| The Clinical Trials Network, LLC | Willoughby | Ohio | 44096 | — |
| The Pennsylvania State University (Penn State) Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Vanderbilt University Medical Center-GI Clinical Research Program | Nashville | Tennessee | 37232 | — |
| Advanced Research Institute - Ogden | Ogden | Utah | 84405 | — |
| Care Access Research | Salt Lake City | Utah | 84124 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05774184, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 30, 2026 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05774184 live on ClinicalTrials.gov.