Study to Assess Adverse Events, Change in Disease Activity, and How Oral Upadacitinib Moves Through the Body of Pediatric Participants With Moderately to Severely Active Ulcerative Colitis.
Public ClinicalTrials.gov record NCT05782907. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Multicenter Study to Evaluate Efficacy, Safety, and Pharmacokinetics of Upadacitinib With Open-Label Induction, Randomized, Double-Blind Maintenance and Open-Label Long-Term Extension in Pediatric Subjects With Moderately to Severely Active Ulcerative Colitis and Inadequate Response, Intolerance, or Medical Contraindications to Corticosteroids, Immunosuppressants, and/or Biologic Therapy
Study identification
- NCT ID
- NCT05782907
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 122 participants
Conditions and interventions
Conditions
Interventions
- Upadacitinib Drug
Drug
Eligibility (public fields only)
- Age range
- 2 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 5, 2023
- Primary completion
- Jul 31, 2028
- Completion
- Sep 30, 2033
- Last update posted
- Dec 25, 2025
2023 – 2033
United States locations
- U.S. sites
- 20
- U.S. states
- 14
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Children's Hospital /ID# 250135 | Phoenix | Arizona | 85016-7710 | — |
| Arkansas Children's Hospital /ID# 250106 | Little Rock | Arkansas | 72202 | — |
| Kindred Medical Institute - Corona /ID# 255484 | Corona | California | 92879-3104 | — |
| UCSF Benioff Children's Hospital - Oakland /ID# 255067 | Oakland | California | 94609 | — |
| Lucile Packard Children's Hospital /ID# 258430 | Palo Alto | California | 94304 | — |
| Children's Hospital Colorado - Aurora /ID# 250110 | Aurora | Colorado | 80045 | — |
| Nemours/Alfred duPont Hospital for Children /ID# 255483 | Wilmington | Delaware | 19803 | — |
| Childrens Healthcare of Atlanta - Center for Advanced Pediatrics /ID# 255069 | Atlanta | Georgia | 30329 | — |
| Ann & Robert H. Lurie Children's Hospital of Chicago /ID# 254505 | Chicago | Illinois | 60611 | — |
| OSF St. Francis Medical Center /ID# 256968 | Peoria | Illinois | 61637-0001 | — |
| Massachusetts General Hospital /ID# 250142 | Boston | Massachusetts | 02114 | — |
| Boston Children's Hospital /ID# 250108 | Boston | Massachusetts | 02115 | — |
| NYU Langone Hospital - Long Island /ID# 250136 | Mineola | New York | 11501 | — |
| The Mount Sinai Hospital /ID# 250141 | New York | New York | 10029 | — |
| Univ NC Chapel Hill /ID# 254541 | Chapel Hill | North Carolina | 27514-4220 | — |
| Levine Children's Hospital /ID# 250131 | Charlotte | North Carolina | 28203 | — |
| UH Cleveland Medical Center /ID# 250134 | Cleveland | Ohio | 44106 | — |
| Children's Hospital of Philadelphia - Main /ID# 258773 | Philadelphia | Pennsylvania | 19104-4319 | — |
| Children's Specialty Group /ID# 256966 | Norfolk | Virginia | 23507 | — |
| University of Wisconsin - Madison /ID# 250632 | Madison | Wisconsin | 53715-1218 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 69 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05782907, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 25, 2025 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05782907 live on ClinicalTrials.gov.