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Active, not recruiting Phase 1 Interventional

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT05787587

Public ClinicalTrials.gov record NCT05787587. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 4:12 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to characterize the safety, tolerability, and efficacy of IDE161 as a single agent and in combination with pembrolizumab.

Study identification

NCT ID
NCT05787587
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
IDEAYA Biosciences
Industry
Enrollment
216 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 17, 2023
Primary completion
Sep 30, 2026
Completion
Apr 30, 2027
Last update posted
Jul 12, 2026

2023 – 2027

United States locations

U.S. sites
27
U.S. states
20
U.S. cities
25
Facility City State ZIP Site status
HonorHealth Research Institute Phoenix Arizona 85027
The Angeles Clinic Los Angeles California 90025
Hoag Memorial Hospital Newport Beach California 92663
California Pacific Medical Center San Francisco California 94115
Sarah Cannon Research Institute Denver Colorado 80218
Yale University New Haven Connecticut 06511
Orlando Health Orlando Florida 32806
Emory University Atlanta Georgia 30322
OSF St Francis Medical Center Peoria Illinois 61637
Indiana University Indianapolis Indiana 46202
Dana Faber Cancer Institute Boston Massachusetts 02215
Karmanos Cancer Institute Detroit Michigan 48201
Comprehensive Cancer Centers of Nevada Las Vegas Nevada 89169
Roswell Park Comprehensive Cancer Center Buffalo New York 14203
Columbia University Medical Center New York New York 10032
Weil Cornell University New York New York 10065
Sarah Cannon Research Institute - Oklahoma University Oklahoma City Oklahoma 73104
University of Pennsylvania Philadelphia Pennsylvania 19104
Sarah Cannon Research Institute - Thomas Jefferson University Philadelphia Pennsylvania 19107
Sarah Cannon Research Institute Nashville Tennessee 37203
MD Anderson Houston Texas 77030
NEXT Oncology Irving Texas 75039
NEXT Oncology San Antonio Texas 78229
START Mountain Region West Valley City Utah 84119
NEXT Oncology Fairfax Virginia 22031
Swedish Cancer Institute Seattle Washington 98104
University of Wisconsin Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05787587, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 12, 2026 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05787587 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →