A Study to Understand the Effect and Safety of the Study Medicine PF-07817883 in Adults Who Have Symptoms of COVID-19 But Are Not Hospitalized
Public ClinicalTrials.gov record NCT05799495. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 2B, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, PARALLEL GROUP, DOSE RANGING STUDY TO EVALUATE VIROLOGICAL RESPONSE AND SAFETY OF ORAL PF-07817883 IN NON-HOSPITALIZED SYMPTOMATIC ADULT PARTICIPANTS WITH COVID-19
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to understand the effects and safety of PF-07817883 treatment. The study wants to know how PF-07817883 treatment lowers the level of the virus that causes COVID 19. To understand that samples are collected from adult participants who have the symptoms of COVID 19 but are not hospitalized. The study is seeking for participants who: * are 18 years of age or older at the time of entering the study. * have a positive rapid antigen test within 48 hours before entering the study. Rapid antigen test is a test done to confirm the presence of a specific virus in the body. * have onset of signs or symptoms of COVID-19 within 5 days before entering the study. * have at least 1 of the specified signs or symptoms of COVID-19 present on the day of entering the study. Around 228 participants with a confirmed case of COVID 19 are planned to be taken into the study. Participants will be randomly grouped to receive PF-07817883. Three groups will receive 100, 300, 600mg of PF-07817883 and one of the groups will receive placebo (a pill that doesn't have any medicines) orally every 12 hours for 5 days. The study is going to last up to 5 weeks. This includes the initial period of selecting participants, participants receiving the medicine or the placebo and then a 4-week follow-up period after giving the participants the last medicine. The study team will monitor how each participant is doing with the study treatment during the study.
Study identification
- NCT ID
- NCT05799495
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 240 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 23, 2023 (Actual)
- Primary completion
- Sep 13, 2023 (Actual)
- Completion
- Oct 11, 2023 (Actual)
- Last update posted
- Oct 9, 2024
2023
United States locations
- U.S. sites
- 53
- U.S. states
- 16
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cullman Clinical Trials | Cullman | Alabama | 35055 | — |
| ClinMed | Phoenix | Arizona | 85004 | — |
| Epic Medical Research - Surprise | Surprise | Arizona | 85378 | — |
| Applied Research Center of Arkansas | Little Rock | Arkansas | 72212 | — |
| Franco Felizarta, Md | Bakersfield | California | 93301 | — |
| Hope Clinical Research, Inc. | Canoga Park | California | 91303 | — |
| Velocity Clinical Research, Chula Vista | Chula Vista | California | 91911 | — |
| Benchmark Research | Colton | California | 92324 | — |
| Ascada Health PC dba Ascada Research | Fullerton | California | 92835 | — |
| Long Beach Clinical Trials | Long Beach | California | 90806 | — |
| Marvel Clinical Research - Santa Ana | Santa Ana | California | 92704 | — |
| Herco Medical and Research Center Inc | Coral Gables | Florida | 33134 | — |
| Advance Clinical Research Group | Cutler Bay | Florida | 33157 | — |
| Proactive Clinical Research,LLC | Fort Lauderdale | Florida | 33308 | — |
| Qway Research LLC | Hialeah | Florida | 33010 | — |
| Unlimited Medical Research Group LLC | Hialeah Gardens | Florida | 33018 | — |
| Angels Clinical Research Institute | Miami | Florida | 33122 | — |
| South Florida Research Center | Miami | Florida | 33135 | — |
| USPA Advance Concept Medical Research Group | Miami | Florida | 33143 | — |
| Bio-Medical Research LLC | Miami | Florida | 33144 | — |
| Coral Research Clinic Corp | Miami | Florida | 33186 | — |
| Palm Springs Community Health Center | Miami Lakes | Florida | 33014 | — |
| DBC Research USA | Pembroke Pines | Florida | 33029 | — |
| GCP Research, Global Clinical professionals | St. Petersburg | Florida | 33705 | — |
| Javara - Privia Medical Group Georgia - Albany | Albany | Georgia | 31707 | — |
| Centricity Research Columbus Georgia Multispecialty | Columbus | Georgia | 31904 | — |
| Centricity Research Columbus Acute Care | Columbus | Georgia | 31909 | — |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | 30291 | — |
| Snake River Research | Idaho Falls | Idaho | 83404 | — |
| University of Massachusetts Chan Medical School | Worcester | Massachusetts | 01655 | — |
| Great Lakes Research Group, Inc. | Bay City | Michigan | 48706 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| Henderson Clinical Trials | Henderson | Nevada | 89052 | — |
| Excel Clinical Research, LLC | Las Vegas | Nevada | 89109 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Accellacare - Wilmington | Wilmington | North Carolina | 28401 | — |
| Wellnow Urgent Care and Research | Cincinnati | Ohio | 45215 | — |
| Remington-Davis, Inc | Columbus | Ohio | 43215 | — |
| WellNow Urgent Care & Research | Dayton | Ohio | 45424 | — |
| Kur Research @ Bon Secours Mercy Health, Inc - Urgent Care Easley | Easley | South Carolina | 29640 | — |
| Javara - Privia Medical Group Gulf Coast - The Woodlands PGTW | Conroe | Texas | 77384 | — |
| Javara - Privia Medical Group Gulf Coast - Cypress | Cypress | Texas | 77433 | — |
| DFW Clinical Research | Dallas | Texas | 75234 | — |
| Proactive Clinical Research LLC | Edinburg | Texas | 78539 | — |
| Next Level Urgent Care | Houston | Texas | 77057 | — |
| Laguna Clinical Research | Laredo | Texas | 78041 | — |
| Epic Clinical Research | Lewisville | Texas | 75057 | — |
| BFHC Research, LLC | San Antonio | Texas | 78249 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| Javara - Privia Medical Group Gulf Coast - The Woodlands PGTW | Shenandoah | Texas | 77384 | — |
| Javara - Privia Medical Group North Texas - Stephenville | Stephenville | Texas | 76401 | — |
| Javara - Privia Medical Group Gulf Coast - The Woodlands PGTW | The Woodlands | Texas | 77384 | — |
| Eastside Research Associates | Redmond | Washington | 98052 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05799495, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 9, 2024 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05799495 live on ClinicalTrials.gov.