ClinicalTrials.gov record
Recruiting Phase 1 Interventional

A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

ClinicalTrials.gov ID: NCT05818683

Public ClinicalTrials.gov record NCT05818683. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 9, 2026, 9:32 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b Study of JNJ-78278343, Targeting Human Kallikrein 2 (KLK2) in Combination With Other Agents for Metastatic Prostate Cancer

Study identification

NCT ID
NCT05818683
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Janssen Research & Development, LLC
Industry
Enrollment
300 participants

Conditions and interventions

Interventions

  • Abiraterone acetate plus prednisone (AAP) Drug
  • Apalutamide Drug
  • Cabazitaxel Drug
  • Cetrelimab Drug
  • Darolutamide Drug
  • Docetaxel Drug
  • Enzalutamide Drug
  • JNJ-101556143 Drug
  • Lutetium Lu-177 vipivotide tetraxetan Drug
  • Pasritamig Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 25, 2023
Primary completion
Aug 30, 2027
Completion
May 22, 2028
Last update posted
May 7, 2026

2023 – 2028

United States locations

U.S. sites
7
U.S. states
5
U.S. cities
7
Facility City State ZIP Site status
Florida Cancer Specialists Sarasota Florida 34232 Recruiting
Start Midwest Grand Rapids Michigan 49546 Recruiting
Washington University School Of Medicine St Louis Missouri 63110 Recruiting
Perlmutter Cancer Center at NYU Langone Brooklyn Brooklyn New York 11223 Recruiting
Laura & Isaac Perlmutter Cancer Center at NYU Langone Hospital - Long Island Mineola New York 11501 Recruiting
NYU Langone Health New York New York 10016 Recruiting
Sidney Kimmel Cancer Center - Jefferson Health Philadelphia Pennsylvania 19107 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05818683, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 7, 2026 · Synced May 9, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05818683 live on ClinicalTrials.gov.

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