A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related Comorbidities
Public ClinicalTrials.gov record NCT05822830. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3b, Randomized Controlled Study to Evaluate the Efficacy and Safety of Tirzepatide Compared to Semaglutide in Adults Who Have Obesity or Overweight With Weight Related Comorbidities
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this phase 3b study is to evaluate the efficacy and safety of tirzepatide compared with semaglutide in adult participants who have obesity or overweight with weight related comorbidities without Type 2 Diabetes. The study will last around 74 weeks.
Study identification
- NCT ID
- NCT05822830
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 751 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 21, 2023 (Actual)
- Primary completion
- Nov 13, 2024 (Actual)
- Completion
- Nov 13, 2024 (Actual)
- Last update posted
- Nov 26, 2025
2023 – 2024
United States locations
- U.S. sites
- 30
- U.S. states
- 18
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cahaba Research | Birmingham | Alabama | 35242 | — |
| Cahaba Research - Pelham | Pelham | Alabama | 35124 | — |
| Southern California Dermatology, Inc. | Santa Ana | California | 92701 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| University Clinical Investigators, Inc. | Tustin | California | 92780 | — |
| Velocity Clinical Research, Hallandale Beach | Hallandale | Florida | 33009 | — |
| New Horizon Research Center | Miami | Florida | 33165 | — |
| ForCare Clinical Research | Tampa | Florida | 33613-1244 | — |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | 30291 | — |
| Rocky Mountain Clinical Research | Idaho Falls | Idaho | 83404 | — |
| Iowa Diabetes and Endocrinology Research Center | West Des Moines | Iowa | 50265 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Arcturus Healthcare , PLC, Troy Internal Medicine Research Division | Troy | Michigan | 48098 | — |
| Prime Health and Wellness/SKYCRNG | Fayette | Mississippi | 39069 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Palm Research Center Tenaya | Las Vegas | Nevada | 89128 | — |
| Palm Research Center Sunset | Las Vegas | Nevada | 89148 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| PharmQuest | Greensboro | North Carolina | 27408 | — |
| Lillestol Research | Fargo | North Dakota | 58104 | — |
| Alliance for Multispecialty Research, LLC | Norman | Oklahoma | 73069 | — |
| Tribe Clinical Research, LLC | Greenville | South Carolina | 29607 | — |
| WR-Clinsearch, LLC | Chattanooga | Tennessee | 37421 | — |
| The University of Texas Health Science Center at Houston | Bellaire | Texas | 77401 | — |
| Dallas Diabetes Research Center | Dallas | Texas | 75230 | — |
| North Texas Endocrine Center | Dallas | Texas | 75231 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77043 | — |
| PlanIt Research, PLLC | Houston | Texas | 77079 | — |
| Southern Endocrinology Associates | Mesquite | Texas | 75149 | — |
| Pinnacle Clinical Research | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05822830, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 26, 2025 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05822830 live on ClinicalTrials.gov.