Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
Public ClinicalTrials.gov record NCT05826535. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2 Multi-Center Study Evaluating the Safety and Efficacy of Rondecabtagene Autoleucel, a CD19/CD20 Dual-Targeting Chimeric Antigen Receptor T-Cell Therapy in Participants With Aggressive B-Cell Non-Hodgkin Lymphoma
Study identification
- NCT ID
- NCT05826535
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Lyell Immunopharma, Inc.
- Industry
- Enrollment
- 270 participants
Conditions and interventions
Conditions
Interventions
- Cyclophosphamide Drug
- Fludarabine Drug
- Rondecabtagene autoleucel (ronde-cel) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 8, 2023
- Primary completion
- Dec 30, 2028
- Completion
- Jun 29, 2031
- Last update posted
- May 6, 2026
2023 – 2031
United States locations
- U.S. sites
- 31
- U.S. states
- 20
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California-Irvine Medical Center | Irvine | California | 92697 | Recruiting |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | Recruiting |
| University of California, Los Angeles (UCLA) Medical Center | Los Angeles | California | 90095 | Recruiting |
| Scripps Clinic | San Diego | California | 92037 | Recruiting |
| Colorado Blood Cancer Institute | Denver | Colorado | 80218 | Recruiting |
| Augusta University Medical Center | Augusta | Georgia | 30912 | Recruiting |
| Indiana Blood and Marrow Transplantation | Indianapolis | Indiana | 46237 | Recruiting |
| University of Iowa | Iowa City | Iowa | 52242 | Recruiting |
| University of Louisville Brown Cancer Center | Louisville | Kentucky | 40202 | Recruiting |
| Louisiana State University Health Sciences Center | Shreveport | Louisiana | 71130 | Recruiting |
| Corewell Health | Grand Rapids | Michigan | 49503 | Recruiting |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | Recruiting |
| John Theurer Cancer Center Hackensack University Medical Center | Hackensack | New Jersey | 07601 | Recruiting |
| University of New Mexico Comprehensive Cancer Center | Albuquerque | New Mexico | 87131 | Recruiting |
| Roswell Park Comprehensive Cancer Center | Buffalo | New York | 14263 | Recruiting |
| David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center | New York | New York | 10021 | Recruiting |
| Montefiore Medical Center | The Bronx | New York | 10461 | Recruiting |
| Atrium Health Wake Forest Baptist | Winston-Salem | North Carolina | 27157 | Recruiting |
| University of Cincinnati (UC) Physicians Company, LLC | Cincinnati | Ohio | 45267 | Recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44195 | Recruiting |
| Lehigh Valley Topper Cancer Center Institute | Allentown | Pennsylvania | 18103 | Recruiting |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | Recruiting |
| West Penn Hospital | Pittsburgh | Pennsylvania | 15224 | Recruiting |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | Recruiting |
| Baylor University Medical Center | Dallas | Texas | 75246 | Recruiting |
| Texas Transplant Institute | San Antonio | Texas | 78229 | Recruiting |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | Recruiting |
| Intermountain Healthcare | Salt Lake City | Utah | 84143 | Recruiting |
| Virginia Oncology Associates | Norfolk | Virginia | 24502 | Recruiting |
| Virginia Commonwealth University-Massey Cancer Center | Richmond | Virginia | 23298 | Recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05826535, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05826535 live on ClinicalTrials.gov.