Incremental Hemodialysis: The TwoPlus Trial
Public ClinicalTrials.gov record NCT05828823. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Comparative Effectiveness of an Individualized Model of Hemodialysis Versus Conventional Hemodialysis
Study identification
- NCT ID
- NCT05828823
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Enrollment
- 350 participants
Conditions and interventions
Conditions
Interventions
- Hemodialysis thrice weekly Other
- Hemodialysis twice weekly Device
Other · Device
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 25, 2024
- Primary completion
- Aug 31, 2027
- Completion
- Feb 29, 2028
- Last update posted
- Jan 28, 2026
2024 – 2028
United States locations
- U.S. sites
- 10
- U.S. states
- 8
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Florida | Jacksonville | Florida | 32209 | Recruiting |
| Emory University | Atlanta | Georgia | 30322 | Recruiting |
| Johns Hopkins University School of Medicine (JHUSM) | Baltimore | Maryland | 21218 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | Recruiting |
| Renal Research Institute (RRI) | New York | New York | 10065 | Recruiting |
| Northwell Health | Queens | New York | 11427 | Recruiting |
| University of North Carolina Chapel Hill | Chapel Hill | North Carolina | 27599 | Recruiting |
| Atrium Health Wake Forest Baptist | Winston-Salem | North Carolina | 27157 | Recruiting |
| University of Virginia (UVA) | Charlottesville | Virginia | 22904 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05828823, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 28, 2026 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05828823 live on ClinicalTrials.gov.