ClinicalTrials.gov record
Recruiting Phase 1Phase 2 Interventional

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

ClinicalTrials.gov ID: NCT05848687

Public ClinicalTrials.gov record NCT05848687. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 7:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Study identification

NCT ID
NCT05848687
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Tanja Andrea Gruber
Other
Enrollment
90 participants

Conditions and interventions

Interventions

  • Blinatumomab Drug
  • Bortezomib Drug
  • Dexamethasone Drug
  • Mercaptopurine Drug
  • Methotrexate Drug
  • Mitoxantrone Drug
  • PEG asparaginase Drug
  • Vorinostat Drug
  • Ziftomenib Drug

Drug

Eligibility (public fields only)

Age range
Up to 1 Year
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 2, 2023
Primary completion
Nov 30, 2028
Completion
Nov 30, 2033
Last update posted
Apr 19, 2026

2023 – 2033

United States locations

U.S. sites
17
U.S. states
12
U.S. cities
17
Facility City State ZIP Site status
Phoenix Children's Hospital Phoenix Arizona 85016 Recruiting
Arkansas Children's Hospital Little Rock Arkansas 72202 Recruiting
Children's Hospital Los Angeles Los Angeles California 90027 Recruiting
Valley Children's Hospital Madera California 93636 Recruiting
Children's Hospital of Orange County Orange California 92868 Recruiting
Stanford University Palo Alto California 94304 Recruiting
Rady Children's Hospital San Diego San Diego California 92123 Not yet recruiting
Arnold Palmer Hospital for Children Orlando Florida 32806 Recruiting
Children's Hospital of Minnesota Minneapolis Minnesota 55404 Recruiting
Memorial Sloan Kettering Cancer Center New York New York 10065 Recruiting
Novant Health - Hemby Children's Hospital Charlotte North Carolina 28204 Not yet recruiting
Doernbecher Children's Hospital Portland Oregon 97239 Recruiting
Penn State Milton S Hershey Medical Center Hershey Pennsylvania 17033-0850 Not yet recruiting
MD Anderson Houston Texas 77030 Recruiting
University of Texas Health Science Center San Antonio San Antonio Texas 78229 Recruiting
University of Utah Huntsman Cancer Institute Salt Lake City Utah 84108 Not yet recruiting
Children's Hospital of The King's Daughters Norfolk Virginia 23507 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05848687, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 19, 2026 · Synced May 8, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05848687 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →