A Switch Study From High-Sodium Oxybate to Xywav to Evaluate Changes in Blood Pressure in Participants With Narcolepsy
Public ClinicalTrials.gov record NCT05869773. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Multicenter Switch Study Evaluating Changes in Blood Pressure in Participants With Narcolepsy Switching From High-Sodium Oxybate to Xywav
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The aim of this study is to quantify the change in blood pressure when participants with narcolepsy treated with high-sodium oxybate are transitioned to Xywav, a low-sodium oxybate. The results of this study may provide health care providers (HCPs), patients, and payers with important new information regarding BP changes related to differences in sodium content between available oxybates for the treatment of narcolepsy.
Study identification
- NCT ID
- NCT05869773
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 155 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 26, 2023 (Actual)
- Primary completion
- Feb 25, 2025 (Actual)
- Completion
- Mar 10, 2025 (Actual)
- Last update posted
- Apr 24, 2026
2023 – 2025
United States locations
- U.S. sites
- 31
- U.S. states
- 16
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Science 37 | Culver City | California | 90230 | — |
| M3 Wake Research | Encino | California | 91436 | — |
| So Cal Clinical Research | Huntington Beach | California | 92647 | — |
| Long Beach Research Institute | Lakewood | California | 90805 | — |
| Stanford School of Medicine | Redwood City | California | 94063 | — |
| TriValley Sleep Center | San Ramon | California | 94583 | — |
| SDS Clinical Trials, Inc. | Santa Ana | California | 92705 | — |
| FWD Clinical Research | Boca Raton | Florida | 33486 | — |
| Meris Clinical Research, LLC | Brandon | Florida | 33511 | — |
| Ocean Wellness Center | Miami | Florida | 33169 | — |
| Serenity Research Center LLC | Miami | Florida | 33176 | — |
| Florida Pediatric Research Institute, LLC | Orlando | Florida | 32804 | — |
| Sleep Practitioners, LLC | Macon | Georgia | 31210 | — |
| Saltzer Medical Group | Nampa | Idaho | 83686 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Neurocare, Inc | Newton | Massachusetts | 02459 | — |
| Sparrow Health System | Lansing | Michigan | 48911 | — |
| Bryan Medical Center | Lincoln | Nebraska | 68506 | — |
| Henderson Clinical Trials LLC | Henderson | Nevada | 89052 | — |
| Advanced Respiratory and Sleep Medicine, PLLC | Huntersville | North Carolina | 28078 | — |
| Intrepid Research, LLC | Cincinnati | Ohio | 45245 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Ohio Sleep Medicine and Neuroscience | Dublin | Ohio | 43017 | — |
| OHSU Hospital | Portland | Oregon | 97239 | — |
| Abington Neurological Associates, LTD | Abington | Pennsylvania | 19001 | — |
| Bogan Sleep Consultants, LLC | Columbia | South Carolina | 29201 | — |
| Velocity Clinical Research, Greenville | Greenville | South Carolina | 29615 | — |
| Clinical Research of Rock Hill | Rock Hill | South Carolina | 29732 | — |
| FutureSearch Trials of Neurology | Austin | Texas | 78731 | — |
| Sleep Therapy & Research Center | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05869773, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 24, 2026 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05869773 live on ClinicalTrials.gov.