A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
Public ClinicalTrials.gov record NCT05869903. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind Study to Investigate the Efficacy and Safety of Once-Daily Oral Orforglipron Compared With Placebo in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-1)
Study identification
- NCT ID
- NCT05869903
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 3,127 participants
Conditions and interventions
Conditions
Interventions
- Orforglipron Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 4, 2023
- Primary completion
- Jul 24, 2025
- Completion
- Sep 30, 2027
- Last update posted
- Nov 4, 2025
2023 – 2027
United States locations
- U.S. sites
- 43
- U.S. states
- 19
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Institute for Liver Health II dba Arizona Clinical Trials - Mesa | Chandler | Arizona | 85225 | — |
| Clinical Research Institute of Arizona (CRI) - Sun City West | Sun City West | Arizona | 85375 | — |
| John Muir Physician Network Research Center | Concord | California | 94520 | — |
| AMCR Institute | Escondido | California | 92025 | — |
| NorCal Medical Research, Inc | Greenbrae | California | 94904 | — |
| Velocity Clinical Research, Huntington Park | Huntington Park | California | 90255 | — |
| Velocity Clinical Research, Westlake | Los Angeles | California | 90057 | — |
| Catalina Research Institute, LLC | Montclair | California | 91763 | — |
| Norcal Endocrinology & Internal Medicine | San Ramon | California | 94583 | — |
| University Clinical Investigators, Inc. | Tustin | California | 92780 | — |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| New Age Medical Research Corporation | Miami | Florida | 33186 | — |
| South Broward Research | Miramar | Florida | 33027 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Jedidiah Clinical Research - Tampa - Bay Plaza | Tampa | Florida | 33619 | — |
| Clinical Site Partners, LLC dba Flourish Research | Winter Park | Florida | 32789 | — |
| Physicians Research Associates | Lawrenceville | Georgia | 30046 | — |
| East Coast Institute for Research, LLC | Macon | Georgia | 31210 | — |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | 30291 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Elite Clinical Trials | Blackfoot | Idaho | 83221 | — |
| Cotton O'Neil Clinical Research Center | Topeka | Kansas | 66606 | — |
| Cotton O'Neil Diabetes & Endocrinology | Topeka | Kansas | 66606 | — |
| Pennington Biomedical Research Center | Baton Rouge | Louisiana | 70808 | — |
| Care Access - Lake Charles | Lake Charles | Louisiana | 70601 | — |
| MedStar Health Research Institute (MedStar Physician Based Research Network) | Hyattsville | Maryland | 20782 | — |
| Endocrine and Metabolic Consultants | Rockville | Maryland | 20852 | — |
| Arcturus Healthcare , PLC, Troy Internal Medicine Research Division | Troy | Michigan | 48098 | — |
| SKY Integrative Medical Center/SKYCRNG | Ridgeland | Mississippi | 39157 | — |
| Las Vegas Medical Research | Las Vegas | Nevada | 89128 | — |
| Long Island Cardiovascular Consultants | Lake Success | New York | 11042 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| Alliance for Multispecialty Research, LLC | Norman | Oklahoma | 73069 | — |
| Texas Diabetes & Endocrinology, P.A. | Austin | Texas | 78731 | — |
| Thyroid, Endocrinology, and Diabetes | Dallas | Texas | 75208 | — |
| Velocity Clinical Research, Dallas | Dallas | Texas | 75230 | — |
| Cedar Health Research | Dallas | Texas | 75251 | — |
| Juno Research | Houston | Texas | 77054 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| Soma Clinical Trials | Wylie | Texas | 75098 | — |
| Physicians' Research Options | Draper | Utah | 84020 | — |
| Health Research of Hampton Roads, Inc. | Newport News | Virginia | 23606 | — |
| Eastside Research Associates | Redmond | Washington | 98052 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 95 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05869903, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 4, 2025 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05869903 live on ClinicalTrials.gov.