Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab
Public ClinicalTrials.gov record NCT05877963. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Evaluating Safety, Efficacy and Pharmacokinetics of a Modified Regimen of Ublituximab (ENHANCE )
Study identification
- NCT ID
- NCT05877963
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- TG Therapeutics, Inc.
- Industry
- Enrollment
- 800 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- Ublituximab Biological
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 12, 2023
- Primary completion
- Nov 30, 2027
- Completion
- Nov 30, 2027
- Last update posted
- Apr 1, 2026
2023 – 2027
United States locations
- U.S. sites
- 35
- U.S. states
- 25
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| TG Therapeutics Investigational Trial Site | Birmingham | Alabama | 35209 | Recruiting |
| TG Therapeutics Investigational Trial Site | Cullman | Alabama | 35058 | Recruiting |
| TG Therapeutics Investigational Trial Site | Orange | California | 92697 | Recruiting |
| TG Investigational Site | Fort Collins | Colorado | 80528 | Recruiting |
| TG Therapeutics Investigational Trial Site | Washington D.C. | District of Columbia | 20007 | Recruiting |
| TG Therapeutics Investigational Trial Site | Tampa | Florida | 33612 | Recruiting |
| TG Therapeutics Investigational Trial Site | Chicago | Illinois | 60612 | Recruiting |
| TG Therapeutics Investigational Trial Site | Indianapolis | Indiana | 46256 | Recruiting |
| TG Therapeutics Investigational Trial Site | Iowa City | Iowa | 52242 | Recruiting |
| TG Therapeutics Investigational Trial Site | Overland Park | Kansas | 66212 | Recruiting |
| TG Therapeutics Investigational Trial Site | Lutherville | Maryland | 21093 | Recruiting |
| TG Therapeutics Investigational Trial Site | Boston | Massachusetts | 00002 | Recruiting |
| TG Therapeutics Investigational Trial Site | Foxborough | Massachusetts | 02035 | Recruiting |
| TG Therapeutics Investigational Trial Site | North Worcester | Massachusetts | 01655 | Recruiting |
| TG Therapeutics Investigational Trial Site | Wellesley | Massachusetts | 02481uni | Recruiting |
| TG Investigational Site | Farmington | Michigan | 48334 | Recruiting |
| TG Therapeutics Investigational Trial Site | Golden Valley | Minnesota | 55422 | Recruiting |
| TG Therapeutics Investigational Trial Site | Plymouth | Minnesota | 55446 | Recruiting |
| TG Therapeutics Investigational Trial Site | St Louis | Missouri | 63131 | Recruiting |
| TG Therapeutics Investigational Trial Site | New York | New York | 10025 | Recruiting |
| TG Therapeutics Investigational Trial Site | New York | New York | 11021 | Recruiting |
| TG Therapeutics Investigational Trial SiteCharlotte | Charlotte | North Carolina | 28204 | Recruiting |
| TG Therapeutics Investigational Trial Site | Raleigh | North Carolina | 27607 | Recruiting |
| TG Therapeutics Investigational Trial Site | Cleveland | Ohio | 44195 | Recruiting |
| TG Therapeutics Investigational Trial Site | Dayton | Ohio | 45417 | Recruiting |
| TG Therapeutics Investigational Trial Site | Oklahoma City | Oklahoma | 73104 | Recruiting |
| TG Therapeutics Investigational Trial Site | Greenville | South Carolina | 29605 | Recruiting |
| TG Therapeutics Investigational Trial Site | Knoxville | Tennessee | 37922 | Recruiting |
| TG Therapeutics Investigational Trial Site | Houston | Texas | 77030 | Active, not recruiting |
| TG Therapeutics Investigational Trial Site | Salt Lake City | Utah | 84103 | Recruiting |
| TG Therapeutics Investigational Trial Site | Vienna | Virginia | 22182 | Recruiting |
| TG Therapeutics Investigational Trial Site | Kirkland | Washington | 98034 | Recruiting |
| TG Therapeutics Investigational Trial Site | Seattle | Washington | 98109 | Recruiting |
| TG Therapeutics Investigational Trial Site | Spokane | Washington | 99208 | Recruiting |
| TG Therapeutics Investigational Trial Site | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05877963, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 1, 2026 · Synced Apr 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05877963 live on ClinicalTrials.gov.