Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM Trial

ClinicalTrials.gov ID: NCT05886036

Public ClinicalTrials.gov record NCT05886036. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 7, 2026, 12:12 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

NORM: Nodular Lymphocyte-Predominant Hodgkin Lymphoma Patients Treated in a Randomized Phase 2 Trial With Either Rituximab or Mosunetuzumab

Study identification

NCT ID: NCT05886036
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: National Cancer Institute (NCI); NIH
Enrollment: 70 participants

Conditions and interventions

Conditions

Interventions

Biopsy Procedure Procedure
Biospecimen Collection Procedure
Bone Marrow Biopsy Procedure
Computed Tomography Procedure
Fludeoxyglucose F-18 Other
Mosunetuzumab Biological
Positron Emission Tomography Procedure
Rituximab Biological
Rituximab and Hyaluronidase Human Biological

Procedure · Other · Biological

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jan 22, 2024
Primary completion: Oct 30, 2026
Completion: Oct 30, 2026
Last update posted: May 3, 2026

2024 – 2026

United States locations

U.S. sites: 35
U.S. states: 14
U.S. cities: 33

Facility	City	State	ZIP	Site status
City of Hope Comprehensive Cancer Center	Duarte	California	91010	Recruiting
UM Sylvester Comprehensive Cancer Center at Aventura	Aventura	Florida	33180	Recruiting
UM Sylvester Comprehensive Cancer Center at Coral Gables	Coral Gables	Florida	33146	Recruiting
UM Sylvester Comprehensive Cancer Center at Coral Springs	Coral Springs	Florida	33065	Recruiting
UM Sylvester Comprehensive Cancer Center at Deerfield Beach	Deerfield Beach	Florida	33442	Recruiting
UM Sylvester Comprehensive Cancer Center at Doral	Doral	Florida	33166	Recruiting
UM Sylvester Comprehensive Cancer Center at Hollywood	Hollywood	Florida	33021	Recruiting
University of Miami Miller School of Medicine-Sylvester Cancer Center	Miami	Florida	33136	Recruiting
UM Sylvester Comprehensive Cancer Center at Kendall	Miami	Florida	33176	Recruiting
UM Sylvester Comprehensive Cancer Center at Plantation	Plantation	Florida	33324	Recruiting
Emory University Hospital/Winship Cancer Institute	Atlanta	Georgia	30322	Recruiting
University of Kansas Cancer Center	Kansas City	Kansas	66160	Recruiting
University of Kansas Cancer Center-Overland Park	Overland Park	Kansas	66210	Recruiting
University of Kansas Hospital-Westwood Cancer Center	Westwood	Kansas	66205	Recruiting
University of Kansas Cancer Center - Briarcliff	Kansas City	Missouri	64116	Recruiting
University of Kansas Cancer Center - North	Kansas City	Missouri	64154	Recruiting
University of Kansas Cancer Center - Lee's Summit	Lee's Summit	Missouri	64064	Recruiting
University of Kansas Cancer Center at North Kansas City Hospital	North Kansas City	Missouri	64116	Suspended
Memorial Sloan Kettering Basking Ridge	Basking Ridge	New Jersey	07920	Recruiting
Memorial Sloan Kettering Monmouth	Middletown	New Jersey	07748	Recruiting
Memorial Sloan Kettering Bergen	Montvale	New Jersey	07645	Recruiting
Memorial Sloan Kettering Commack	Commack	New York	11725	Recruiting
Memorial Sloan Kettering Westchester	Harrison	New York	10604	Recruiting
Memorial Sloan Kettering Cancer Center	New York	New York	10065	Recruiting
Memorial Sloan Kettering Nassau	Uniondale	New York	11553	Recruiting
Wake Forest University Health Sciences	Winston-Salem	North Carolina	27157	Recruiting
University of Cincinnati Cancer Center-UC Medical Center	Cincinnati	Ohio	45219	Recruiting
Ohio State University Comprehensive Cancer Center	Columbus	Ohio	43210	Recruiting
University of Cincinnati Cancer Center-West Chester	West Chester	Ohio	45069	Recruiting
University of Oklahoma Health Sciences Center	Oklahoma City	Oklahoma	73104	Recruiting
University of Pittsburgh Cancer Institute (UPCI)	Pittsburgh	Pennsylvania	15232	Active, not recruiting
M D Anderson Cancer Center	Houston	Texas	77030	Recruiting
Huntsman Cancer Institute/University of Utah	Salt Lake City	Utah	84112	Recruiting
University of Virginia Cancer Center	Charlottesville	Virginia	22908	Recruiting
VCU Massey Comprehensive Cancer Center	Richmond	Virginia	23298	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05886036, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 3, 2026 · Synced May 7, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05886036 live on ClinicalTrials.gov.

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