Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

ClinicalTrials.gov ID: NCT05902169

Public ClinicalTrials.gov record NCT05902169. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 29, 2026, 8:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Open-label, Multicentric, Two-arm Pivotal Trial of SonoCloud-9 Combined With Carboplatin (CBDCA) vs Standard of Care Lomustine (CCNU) or Temozolomide (TMZ) in Patients Undergoing Planned Resection for First Recurrence Glioblastoma.

Study identification

NCT ID: NCT05902169
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: CarThera; Industry
Enrollment: 560 participants

Conditions and interventions

Conditions

Interventions

Carboplatin Drug
Lomustine Drug
SonoCloud-9 (SC9) Device
Temozolomide Drug

Drug · Device

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jan 28, 2024
Primary completion: Jan 27, 2028
Completion: Jun 29, 2028
Last update posted: Apr 23, 2026

2024 – 2028

United States locations

U.S. sites: 19
U.S. states: 14
U.S. cities: 17

Facility	City	State	ZIP	Site status
Mayo Clinic Arizona	Phoenix	Arizona	805054	Active, not recruiting
University of California, San Francisco	San Francisco	California	94143	Active, not recruiting
UCHealth	Aurora	Colorado	80011	Active, not recruiting
Mayo Clinic of Jacksonville Florida	Jacksonville	Florida	32224	Active, not recruiting
Miami Cancer Institute	Miami	Florida	33176	Active, not recruiting
Moffitt Cancer Center	Tampa	Florida	33612	Active, not recruiting
Winship Cancer Institute at Emory University	Atlanta	Georgia	30322	Active, not recruiting
Northwestern University	Chicago	Illinois	60611	Active, not recruiting
Indiana University Health	Indianapolis	Indiana	46202	Active, not recruiting
John Hopkins University	Baltimore	Maryland	21287	Active, not recruiting
Mayo Clinic Rochester	Rochester	Minnesota	55905	Active, not recruiting
Weill Cornell Medicine	New York	New York	10021	Active, not recruiting
NewYork-Presbyterian / Columbia University Irving Medical Center	New York	New York	10032	Active, not recruiting
Lennox Hill Hospital	New York	New York	10075	Active, not recruiting
University of North Carolina	Chapel Hill	North Carolina	27516	Active, not recruiting
Penn State Health Milton S. Hershey Medical Center	Hershey	Pennsylvania	17033	Active, not recruiting
University of Texas Southwestern Medical Center	Dallas	Texas	75390	Active, not recruiting
University of Texas Houston Health Science Center	Houston	Texas	77030	Active, not recruiting
University of Utah, Hunstman Cancer Institute	Salt Lake City	Utah	84112	Active, not recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05902169, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 23, 2026 · Synced Apr 29, 2026

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The complete protocol, eligibility criteria, and contact information for NCT05902169 live on ClinicalTrials.gov.

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