SAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects
Public ClinicalTrials.gov record NCT05902962. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 Open-Label, Single Arm Dose Escalation Study to Evaluate the Safety and Tolerability of Intravitreally Administered VP-001 in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy
Study identification
- NCT ID
- NCT05902962
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- PYC Therapeutics
- Industry
- Enrollment
- 17 participants
Conditions and interventions
Interventions
- VP-001 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 19, 2023
- Primary completion
- Oct 7, 2025
- Completion
- Oct 7, 2025
- Last update posted
- Apr 12, 2026
2023 – 2025
United States locations
- U.S. sites
- 6
- U.S. states
- 4
- U.S. cities
- 6
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Florida Health | Jacksonville | Florida | 32209 | — |
| Bascom Palmer Eye Institute University of Miami | Miami | Florida | 33136 | — |
| University of Michigan Kellogg Eye Center | Ann Arbor | Michigan | 48105 | — |
| Oregon Health and Science University - Casey Eye Institute | Portland | Oregon | 97239 | — |
| Retina Foundation of the Southwest | Dallas | Texas | 75321 | — |
| Baylor College of Medicine- Alkek Eye Center | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05902962, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 12, 2026 · Synced May 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05902962 live on ClinicalTrials.gov.