FOG-001 in Locally Advanced or Metastatic Solid Tumors
Public ClinicalTrials.gov record NCT05919264. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2 Study of FOG-001 in Participants With Locally Advanced or Metastatic Solid Tumors
Study identification
- NCT ID
- NCT05919264
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Parabilis Medicines, Inc.
- Industry
- Enrollment
- 595 participants
Conditions and interventions
Conditions
- Adamantinomatous Craniopharyngioma
- Cancer
- Colorectal Cancer
- Desmoid
- Endometrial Carcinoma
- FAP
- HCC
- Locally Advanced Solid Tumor
- Metastatic Cancer
- Metastatic Castration-resistant Prostate Cancer
- Microsatellite Instability-High Colorectal Cancer
- Microsatellite Stable Colorectal Cancer
- Prostate Cancer
- Solid Tumor
- WNT Pathway
Interventions
- Bevacizumab Drug
- FOG-001 Drug
- Nivolumab Drug
- Trifluridine/tipiracil Drug
- mFOLFOX-6 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 22, 2023
- Primary completion
- Mar 31, 2027
- Completion
- Aug 30, 2027
- Last update posted
- May 4, 2026
2023 – 2027
United States locations
- U.S. sites
- 26
- U.S. states
- 18
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Honor Health | Scottsdale | Arizona | 85258 | Recruiting |
| Arizona Cancer Center at University of Arizona | Tucson | Arizona | 85719 | Recruiting |
| University of California, Los Angeles (UCLA) | Los Angeles | California | 90095 | Recruiting |
| Stanford Cancer Institute, Stanford University | Palo Alto | California | 94304 | Recruiting |
| University of California San Francisco, Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94158 | Recruiting |
| Sarcoma Oncology Center | Santa Monica | California | 90403 | Recruiting |
| University of Colorado | Aurora | Colorado | 80045 | Recruiting |
| Yale University School of Medicine | New Haven | Connecticut | 06520 | Recruiting |
| Johns Hopkins University, Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | Recruiting |
| Florida Cancer Specialists | Lake Mary | Florida | 32746 | Terminated |
| Johns Hopkins University, The Sidney Kimmel Comprehensive Cancer Center | Baltimore | Maryland | 21287 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| M Health Fairview University of Minnesota Medical Center | Minneapolis | Minnesota | 55455 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| University Hospitals Cleveland Medical Center, Seidman Cancer Center | Cleveland | Ohio | 44106 | Recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44195 | Recruiting |
| Oregon Health and Science University | Portland | Oregon | 97239 | Recruiting |
| University of Pittsburgh Medical Center, Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | Recruiting |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | Recruiting |
| Vanderbilt Ingram Cancer Center | Nashville | Tennessee | 37232 | Recruiting |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| South Texas Accelerated Research Therapeutics, LLC | San Antonio | Texas | 78229 | Recruiting |
| University of Virginia | Charlottesville | Virginia | 22908 | Recruiting |
| University of Wisconsin, Carbone Cancer Center | Madison | Wisconsin | 53705 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05919264, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2026 · Synced May 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05919264 live on ClinicalTrials.gov.