A 2-part Study Consisting of Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Masked Study to Assess the Safety and Efficacy of Intravitreal (IVT) EYE103 in Patients With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD)
Public ClinicalTrials.gov record NCT05919693. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 2-part Study Consisting of an Open-label Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Single-masked Comparative Safety and Preliminary Efficacy Study of Intravitreal (IVT) EYE103 in a Mixed Population of Participants With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD)
Study identification
- NCT ID
- NCT05919693
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- EyeBiotech Ltd.
- Industry
- Enrollment
- 33 participants
Conditions and interventions
Interventions
- EYE103 Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 11, 2023
- Primary completion
- Aug 25, 2024
- Completion
- Aug 25, 2024
- Last update posted
- Nov 19, 2025
2023 – 2024
United States locations
- U.S. sites
- 27
- U.S. states
- 10
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix, AZ | Phoenix | Arizona | 85032 | — |
| Bakersfield, CA | Bakersfield | California | 93309 | — |
| Modesto, CA | Modesto | California | 95356 | — |
| Mountain View, CA | Mountain View | California | 94040 | — |
| Sacramento, CA | Sacramento | California | 95825 | — |
| Sacramento, CA | Sacramento | California | 95841 | — |
| Colorado Springs, Colorado | Colorado Springs | Colorado | 80909 | — |
| Lakewood, CO | Lakewood | Colorado | 80288 | — |
| Pompano Beach | Pompano Beach | Florida | 33064 | — |
| Lemont, NV | Lemont | Illinois | 60439 | — |
| Hagerstown, MD | Hagerstown | Maryland | 21740 | — |
| Reno, NV | Reno | Nevada | 89502 | — |
| West Columbia, SC | West Columbia | South Carolina | 29169 | — |
| Germantown, TN | Germantown | Tennessee | 38138 | — |
| Knoxville, TN | Knoxville | Tennessee | 37922 | — |
| Nashville, TN | Nashville | Tennessee | 37203 | — |
| Abilene, TX | Abilene | Texas | 79606 | — |
| Amarillo, TX | Amarillo | Texas | 79109 | — |
| Austin, TX | Austin | Texas | 78705 | — |
| Bellaire, TX | Bellaire | Texas | 77401 | — |
| Dallas, TX | Dallas | Texas | 75231 | — |
| Katy, TX | Katy | Texas | 77494 | — |
| McAllen, TX | McAllen | Texas | 78503 | — |
| Plano, TX | Plano | Texas | 75075 | — |
| Round Rock, TX | Round Rock | Texas | 78681 | — |
| San Antonio, TX | San Antonio | Texas | 78240 | — |
| The Woodlands, TX | The Woodlands | Texas | 77384 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05919693, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 19, 2025 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05919693 live on ClinicalTrials.gov.