A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy
Public ClinicalTrials.gov record NCT05923866. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Double-blind, Placebo-controlled, Parallel-group Study Followed by an Open-label, Parallel Group Extension Part to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Potential Efficacy of Multiple Doses of ONO-2808 in Patients With Multiple System Atrophy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2, double-blind, parallel-group, placebo-controlled study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of multiple doses of ONO-2808 in patients with MSA. This is the first study of ONO-2808 in patients with MSA.
Study identification
- NCT ID
- NCT05923866
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 92 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 30 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 22, 2023 (Actual)
- Primary completion
- Sep 15, 2025 (Actual)
- Completion
- Oct 31, 2027 (Estimated)
- Last update posted
- Oct 6, 2026
2023 – 2027
United States locations
- U.S. sites
- 30
- U.S. states
- 16
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Parkinson's Movement and Disorder Institute | Fountain Valley | California | 92708 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| David Geffen School of Medicine at UCLA | Los Angeles | California | 90095 | — |
| Stanford University School of Medicine | Palo Alto | California | 94304 | — |
| CenExel Rocky Mountain Clinical Research | Englewood | Colorado | 80113 | — |
| Yale School of Medicine - Yale Church Street Research Unit (CRSU) | New Haven | Connecticut | 06519 | — |
| Parkinson's Disease and Movement Disorders Center of Boca Raton | Boca Raton | Florida | 33486 | — |
| Norman Fixel Institute for Neurological Diseases - University of Florida | Gainesville | Florida | 32608 | — |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224 | — |
| University of Miami Miller School of Medicine | Miami | Florida | 33136 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30329 | — |
| University of Kansas Medical Center Research Institute | Kansas City | Kansas | 66160 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan School of Medicine | Ann Arbor | Michigan | 48109 | — |
| Quest Research Institute | Farmington Hills | Michigan | 48334 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| NYU Langone Health - NYU Dysautonomia Center | New York | New York | 10016 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10019 | — |
| Columbia University | New York | New York | 10032 | — |
| University of Cincinnati College of Medicine | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Ohio State University | Columbus | Ohio | 43201 | — |
| Penn State University - Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| The University of Pennsylvania - Pennsylvania Hospital | Philadelphia | Pennsylvania | 19107 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Virginia Commonwealth University Medical Center | Richmond | Virginia | 23298 | — |
| Evergreen Health | Kirkland | Washington | 98034 | — |
| Swedish Neuroscience Institute, Movement Disorders Clinic | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05923866, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 6, 2026 · Synced Oct 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05923866 live on ClinicalTrials.gov.