BCG in Combination With Durvalumab in Adult BCG-naïve, High-risk NMIBC Participants
Public ClinicalTrials.gov record NCT05943106. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase IIIb Open-Label, Single-Arm, Multi-Center, US Study of Bacillus Calmette-Guerin (BCG) Administered in Combination With Durvalumab in Adult BCG-naïve, High-risk Non-Muscle- Invasive Bladder Cancer Participants (PATAPSCO)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to assess the safety, tolerability, and efficacy profile of durvalumab + BCG (induction and maintenance) combination therapy in adult United States participants with a histologically confirmed diagnosis of high-risk non-muscle-invasive bladder cancer (NMIBC), who have received no prior systemic therapy for NMIBC, and who are BCG-naïve.
Study identification
- NCT ID
- NCT05943106
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 100 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 130 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 11, 2023 (Actual)
- Primary completion
- Jun 16, 2025 (Actual)
- Completion
- Mar 31, 2027 (Estimated)
- Last update posted
- Aug 13, 2026
2023 – 2027
United States locations
- U.S. sites
- 19
- U.S. states
- 16
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Phoenix | Arizona | 85054 | — |
| Research Site | Little Rock | Arkansas | 72211 | — |
| Research Site | San Diego | California | 92123 | — |
| Research Site | Lakewood | Colorado | 80228 | — |
| Research Site | Hialeah | Florida | 33016 | — |
| Research Site | Jacksonville | Florida | 32209 | — |
| Research Site | Greenwood | Indiana | 46143 | — |
| Research Site | Wichita | Kansas | 67226 | — |
| Research Site | Baltimore | Maryland | 21203 | — |
| Research Site | Hanover | Maryland | 21076 | — |
| Research Site | Royal Oak | Michigan | 48073 | — |
| Research Site | Troy | Michigan | 48084 | — |
| Research Site | Syracuse | New York | 13210 | — |
| Research Site | Cincinnati | Ohio | 45212 | — |
| Research Site | Bala-Cynwyd | Pennsylvania | 19004-1017 | — |
| Research Site | Myrtle Beach | South Carolina | 29572 | — |
| Research Site | Nashville | Tennessee | 37209 | — |
| Research Site | Austin | Texas | 78759 | — |
| Research Site | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05943106, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 13, 2026 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05943106 live on ClinicalTrials.gov.