Department of Defense PTSD Adaptive Platform Trial - Intervention A - Fluoxetine
Public ClinicalTrials.gov record NCT05948553. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multi-center, Multi-arm, Randomized, Placebo-controlled, Double-blind, Adaptive Platform Study to Evaluate the Safety, Tolerability, and Efficacy of Potential Pharmacotherapeutic Interventions in Active-Duty Service Members, Veterans, and Non-Veteran Civilians With PTSD
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2 randomized, double-blinded, placebo-controlled study that will evaluate multiple potential pharmacotherapeutic interventions for PTSD utilizing an adaptive platform trial design. Intervention A - Fluoxetine will assess the safety and efficacy of fluoxetine in participants with PTSD. Please see NCT05422612 for information on the S-21-02 Master Protocol.
Study identification
- NCT ID
- NCT05948553
- Recruitment status
- Suspended
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2, 2023 (Actual)
- Primary completion
- May 2028 (Estimated)
- Completion
- May 2028 (Estimated)
- Last update posted
- May 20, 2026
2023 – 2028
United States locations
- U.S. sites
- 9
- U.S. states
- 9
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Homestead Associates in Research, Inc. | Miami | Florida | 33032 | — |
| Advanced Discovery Research | Atlanta | Georgia | 30318 | — |
| Tripler Army Medical Center (TAMC) | Tripler AMC | Hawaii | 96859 | — |
| Cincinnati Veteran's Affairs Medical Center | Fort Thomas | Kentucky | 41075 | — |
| Walter Reed National Military Medical Center (WRNMC) | Bethesda | Maryland | 20889-5632 | — |
| Upstate Clinical Research Associates, LLC | Williamsville | New York | 14221 | — |
| Wilford Hall Ambulatory Surgical Center (WHASC) | San Antonio | Texas | 78236 | — |
| Alexander T. Augusta Military Medical Center (ATAMMC): | Fort Belvoir | Virginia | 22060-5285 | — |
| Madigan Army Medical Center | Joint Base Lewis McChord | Washington | 98433 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05948553, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 20, 2026 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05948553 live on ClinicalTrials.gov.