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Terminated Phase 1 Interventional

Study of SGR-2921 in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

ClinicalTrials.gov ID: NCT05961839

Public ClinicalTrials.gov record NCT05961839. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 29, 2026, 6:04 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A First-In-Human, Phase 1, Dose Escalation Study of SGR-2921 as Monotherapy In Subjects With Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate safety and tolerability and to determine the maximum tolerated dose (MTD) and/or recommended dose (RD) of SGR-2921.

Study identification

NCT ID
NCT05961839
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Schrödinger, Inc.
Industry
Enrollment
66 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 26, 2023
Primary completion
Aug 13, 2025
Completion
Sep 8, 2025
Last update posted
Sep 21, 2025

2023 – 2025

United States locations

U.S. sites
12
U.S. states
8
U.S. cities
12
Facility City State ZIP Site status
Colorado Blood Cancer Institute Denver Colorado 80218 —
The University of Kansas Clinical Research Center Fairway Kansas 66205 —
Roswell Park Cancer Institute Buffalo New York 14263 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Cleveland Clinic Foundation Cleveland Ohio 44195 —
The Ohio State University Wexner Medical Center - James Cancer Hospital Columbus Ohio 43210 —
Oncology Associates of Oregon, P.C. Eugene Oregon 97401 —
Oregon Health & Science University - Knight Cancer Institute - Center of Hematologic Malignancies Portland Oregon 97239 —
Thomas Jefferson University, Sidney Kimmel Cancer Center, Clinical Research Organization Philadelphia Pennsylvania 19107 —
TriStar Bone Marrow Transplant, LLC Nashville Tennessee 37203 —
St. David's South Austin Medical Center Austin Texas 78745 —
MD Anderson Cancer Center Houston Texas 77030 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05961839, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 21, 2025 · Synced Sep 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05961839 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →