A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia
Public ClinicalTrials.gov record NCT05963074. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multicohort Study to Customize Ibrutinib Treatment Regimens for Patients With Previously Untreated Chronic Lymphocytic Leukemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of ibrutinib + venetoclax (I+V) and ibrutinib monotherapy regimens in which dosing of ibrutinib is either proactively reduced or reactively modified in response to adverse events (AEs).
Study identification
- NCT ID
- NCT05963074
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 333 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 30, 2024 (Actual)
- Primary completion
- Dec 15, 2027 (Estimated)
- Completion
- Mar 19, 2029 (Estimated)
- Last update posted
- Sep 25, 2026
2024 – 2029
United States locations
- U.S. sites
- 32
- U.S. states
- 17
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Oncology Institute Clinical Research | Cerritos | California | 90703 | — |
| Cancer and Blood Specialty Clinic | Los Alamitos | California | 90720 | — |
| SLO Oncology and Hematology Health Center | San Luis Obispo | California | 93401 | — |
| Providence Medical Foundation | Santa Rosa | California | 95403 | — |
| PIH Health Hospital | Whittier | California | 90602 | — |
| Grand Valley Oncology | Grand Junction | Colorado | 81505 | — |
| Mount Sinai Medical Center Campus | Miami Beach | Florida | 33140-2948 | — |
| The Oncology Institute | North Miami Beach | Florida | 33169 | — |
| Mid Florida Hematology Oncology | Orange | Florida | 32763 | — |
| Boise VA Medical Center | Boise | Idaho | 83702 | — |
| Hope and Healing Cancer Services | Hinsdale | Illinois | 60521 | — |
| Springfield Clinic | Springfield | Illinois | 62702 | — |
| Iowa City VA Health Care System | Iowa City | Iowa | 52246 | — |
| Minnesota Oncology Hematology P A | Minneapolis | Minnesota | 55404 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Hunterdon Hematology Oncology | Flemington | New Jersey | 08822 | — |
| Summit Medical Group | Florham Park | New Jersey | 07932 | — |
| Hematology Oncology Associates of Rockland | Nyack | New York | 10960 | — |
| Southeastern Medical Oncology Center | Goldsboro | North Carolina | 27534 | — |
| Oncology Hematology Care | Cincinnati | Ohio | 45242 | — |
| Willamette Valley Cancer Institute and Research Center | Eugene | Oregon | 97401 | — |
| OHSU Knight Cancer Institute | Portland | Oregon | 97239 | — |
| Renovatio Clinical | El Paso | Texas | 79915 | — |
| Texas Oncology-Fort Worth Cancer Center | Fort Worth | Texas | 76104 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Renovatio Clinical 1 | The Woodlands | Texas | 77380 | — |
| Texas Oncology-Gulf Coast | The Woodlands | Texas | 77380 | — |
| Community Cancer Trials of Utah | Ogden | Utah | 84405 | — |
| Virginia Cancer Specialists | Manassas | Virginia | 20110 | — |
| Virginia Oncology Associates | Virginia Beach | Virginia | 23456 | — |
| VA Puget Sound Healthcare System | Seattle | Washington | 98108 | — |
| Northwest Cancer Specialists PC | Vancouver | Washington | 98684 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05963074, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 25, 2026 · Synced Oct 9, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05963074 live on ClinicalTrials.gov.