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Recruiting Phase 2 Interventional

A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC

ClinicalTrials.gov ID: NCT05968326

Public ClinicalTrials.gov record NCT05968326. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 10, 2026, 12:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Open-Label, Multicenter, Randomized Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Patients With Resected Pancreatic Ductal Adenocarcinoma

Study identification

NCT ID
NCT05968326
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Genentech, Inc.
Industry
Enrollment
260 participants

Conditions and interventions

Interventions

  • Atezolizumab Drug
  • Autogene cevumeran Drug
  • mFOLFIRINOX Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 17, 2023
Primary completion
Dec 31, 2030
Completion
Dec 31, 2030
Last update posted
Apr 12, 2026

2023 – 2031

United States locations

U.S. sites
32
U.S. states
14
U.S. cities
25
Facility City State ZIP Site status
USC Norris Comprehensive Cancer Center Los Angeles California 90033 Recruiting
USC Norris Cancer Center Newport Beach California 92663 Recruiting
University of California, San Francisco (UCSF) San Francisco California 94158-2350 Recruiting
University of California Los Angeles Santa Monica California 90404 Recruiting
St. Francis Hospital and Medical Center Hartford Connecticut 06105 Recruiting
Smilow Cancer Center New Haven Connecticut 06510 Withdrawn
Yale Cancer Center New Haven Connecticut 06520 Recruiting
Smilow Cancer Hospital Care Center at Trumbull Trumbull Connecticut 06611 Recruiting
Northwestern Memorial Hospital Chicago Illinois 60611 Recruiting
Indiana University Health Melvin & Bren Simon Cancer Center Indianapolis Indiana 46202 Recruiting
University of Kentucky Medical Center Lexington Kentucky 40536 Recruiting
Harvard Medical School - Massachusetts General Hospital (MGH) - Cancer Center Boston Massachusetts 02114-2621 Recruiting
Boston Medical Center (BMC) - Cancer Care Center Boston Massachusetts 02118 Recruiting
Henry Ford Health System Detroit Michigan 48202-2610 Recruiting
University of Nebraska Omaha Nebraska 68198-5300 Recruiting
Memorial Sloan Kettering Cancer Center Basking Ridge Basking Ridge New Jersey 07920 Recruiting
Memorial Sloan Kettering Cancer Center Middletown New Jersey 07748 Recruiting
Memorial Sloan Kettering Cancer Center at Bergen Montvale New Jersey 07645 Recruiting
Memorial Sloan Kettering Cancer Center - Commack Commack New York 11725 Recruiting
Memorial Sloan Kettering Cancer Center at Westchester Harrison New York 10604 Recruiting
Northwell Health Lake Success New York 11042 Recruiting
NYU Langone Health New York New York 10016 Recruiting
Mount SInai Medical Center New York New York 10029 Recruiting
Columbia University Medical Center New York New York 10032 Recruiting
MEETH-LHH Northwell Health Cancer Clinical Trials Office at MEETH-LHH New York New York 10065-7471 Recruiting
Memorial Sloan Kettering Cancer Center New York New York 10065 Recruiting
Memorial Sloan Kettering Cancer Center at Nassau Uniondale New York 11553 Recruiting
Duke Cancer Institute Durham North Carolina 27710-4000 Recruiting
University of Cincinnati Cancer Institute Cincinnati Ohio 45219 Recruiting
Rhode Island Hospital Providence Rhode Island 02903 Recruiting
Miriam Hospital Providence Rhode Island 02906 Recruiting
Fred Hutchinson Cancer Research Center Seattle Washington 98109 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 57 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05968326, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 12, 2026 · Synced May 10, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05968326 live on ClinicalTrials.gov.

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