A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors
Public ClinicalTrials.gov record NCT05970497. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2, Open-Label, Multi-Center, Dose Escalation and Expansion Study of KB707 in Subjects With Locally Advanced or Metastatic Solid Tumor Malignancies
Study identification
- NCT ID
- NCT05970497
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Krystal Biotech, Inc.
- Industry
- Enrollment
- 240 participants
Conditions and interventions
Interventions
- KB707 Biological
- KEYTRUDA ®( Pembrolizumab) Drug
- Opdualag Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 30, 2023
- Primary completion
- Jun 30, 2027
- Completion
- Jun 30, 2027
- Last update posted
- May 17, 2025
2023 – 2027
United States locations
- U.S. sites
- 15
- U.S. states
- 11
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA Health | Los Angeles | California | 90095 | Recruiting |
| Mission Dermatology Center | Rancho Santa Margarita | California | 92688 | Recruiting |
| BRCR Global | Weston | Florida | 33326 | Recruiting |
| IU Simon Comprehensive Cancer Center | Indianapolis | Indiana | 46202 | Recruiting |
| Henry Ford Cancer Institute | Detroit | Michigan | 48202 | Recruiting |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | Recruiting |
| Morristown Medical Center / Atlantic Health System | Morristown | New Jersey | 07960 | Recruiting |
| Weill Cornell Medicine-New York-Presbyterian Hospital | New York | New York | 10065 | Recruiting |
| Gabrail Cancer Center Research | Canton | Ohio | 44718 | Recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44195 | Recruiting |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | Recruiting |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | Recruiting |
| Renovatio Clinical - El Paso | El Paso | Texas | 79915 | Recruiting |
| MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| Renovatio Clinical - The Woodlands | The Woodlands | Texas | 77380 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05970497, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 17, 2025 · Synced May 4, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05970497 live on ClinicalTrials.gov.