LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF
Public ClinicalTrials.gov record NCT05983250. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Pulmonary Hypertension Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction (PH-HFpEF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy of TNX-103 (oral levosimendan) compared with placebo in subjects with PH-HFpEF as measured by the change in 6-Minute Walk Distance (6 MWD; Day 1 to Week 12).
Study identification
- NCT ID
- NCT05983250
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 230 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 10, 2024 (Actual)
- Primary completion
- Jun 30, 2026 (Actual)
- Completion
- Oct 30, 2028 (Estimated)
- Last update posted
- Jul 24, 2026
2024 – 2028
United States locations
- U.S. sites
- 40
- U.S. states
- 21
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Tenax Investigational Site | Tucson | Arizona | 85721 | — |
| Tenax Investigational Site | La Jolla | California | 92037 | — |
| Tenax Investigational Site | Los Angeles | California | 90033 | — |
| Tenax Investigational Site | Los Angeles | California | 90048 | — |
| Tenax Investigational Site | Sacramento | California | 95817 | — |
| Tenax Investigational Site | San Francisco | California | 94143 | — |
| Tenax Investigational Site | Torrance | California | 90502 | — |
| Tenax Investigational Site | Jacksonville | Florida | 32224 | — |
| Tenax Investigational Site | Winter Haven | Florida | 33881 | — |
| Tenax Investigational Site | Atlanta | Georgia | 30322 | — |
| Tenax Investigational Site | Chicago | Illinois | 60208 | — |
| Tenax Investigational Site | Chicago | Illinois | 60637 | — |
| Tenax Investigational Site | Galesburg | Illinois | 61401 | — |
| Tenax Investigational Site | Indianapolis | Indiana | 46202 | — |
| Tenax Investigational Site | Indianapolis | Indiana | 46260 | — |
| Tenax Investigational Site | Louisville | Kentucky | 40202 | — |
| Tenax Investigational Site | Boston | Massachusetts | 02114 | — |
| Tenax Investigational Site | Minneapolis | Minnesota | 55455 | — |
| Tenax Investigational Site | Rochester | Minnesota | 55905 | — |
| Tenax Investigational Site | St Louis | Missouri | 63136 | — |
| Tenax Investigational Site | Omaha | Nebraska | 68198 | — |
| Tenax Investigational Site | New York | New York | 10021 | — |
| Tenax Investigational Site | New York | New York | 10029 | — |
| Tenax Investigational Site | Rochester | New York | 14621 | — |
| Tenax Investigational Site | Roslyn | New York | 11576 | — |
| Tenax Investigational Site | Durham | North Carolina | 27710 | — |
| Tenax Investigational Site | Greensboro | North Carolina | 27401 | — |
| Tenax Investigational Site | Cincinnati | Ohio | 45267 | — |
| Tenax Investigational Site | Columbus | Ohio | 43214 | — |
| Tenax Investigational Site | Pittsburgh | Pennsylvania | 15212 | — |
| Tenax Investigational Site | Providence | Rhode Island | 02903 | — |
| Tenax Investigational Site | Charleston | South Carolina | 29425 | — |
| Tenax Investigational Site | Columbia | South Carolina | 29044 | — |
| Tenax Investigational Site | Dallas | Texas | 75204 | — |
| Tenax Investigational Site | Dallas | Texas | 75390 | — |
| Tenax Investigational Site | Lubbock | Texas | 79430 | — |
| Tenax Investigational Site | Plano | Texas | 75093 | — |
| Tenax Investigational Site | Murray | Utah | 84107 | — |
| Tenax Investigational Site | Richmond | Virginia | 23298 | — |
| Tenax Investigational Site | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05983250, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 24, 2026 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05983250 live on ClinicalTrials.gov.