A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors
Public ClinicalTrials.gov record NCT05985161. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center Phase II Study of Selinexor in Treating Recurrent or Refractory Wilms Tumor and Other Pediatric Solid Tumors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to find out whether selinexor is an effective treatment for people who have a relapsed/refractory Wilms tumor, rhabdoid tumor, MPNST, BCOR-driven sarcoma, or another solid tumor that makes a higher than normal amount of XPO1 or has genetic changes that increase the activity of XP01.
Study identification
- NCT ID
- NCT05985161
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 45 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Months and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2023
- Primary completion
- Jul 31, 2029
- Completion
- Jul 31, 2029
- Last update posted
- May 5, 2026
2023 – 2029
United States locations
- U.S. sites
- 16
- U.S. states
- 10
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's Hospital of Los Angeles (Data Collection Only) | Los Angeles | California | 90027 | Recruiting |
| Stanford Medicine Children's Health (Data Collection Only) | Palo Alto | California | 94304 | Recruiting |
| Children's National Hospital (Data Collection Only) | Washington D.C. | District of Columbia | 20010 | Recruiting |
| Children's Healthcare of Atlanta (Data Collection and Specimen Analysis) | Atlanta | Georgia | 30322 | Recruiting |
| Ann & Robert H. Lurie Children'S Hospital of Chicag | Chicago | Illinois | 60611 | Recruiting |
| Dana Farber Cancer Institute (Data Collection Only) | Boston | Massachusetts | 02115 | Recruiting |
| Washington University | St Louis | Missouri | 63110 | Recruiting |
| Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities) | Basking Ridge | New Jersey | 07920 | Recruiting |
| Memorial Sloan Kettering Monmouth (Limited Protocol Activities) | Middletown | New Jersey | 07748 | Recruiting |
| Memorial Sloan Kettering Bergen (Limited protocol activities) | Montvale | New Jersey | 07645 | Recruiting |
| Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities ) | Commack | New York | 11725 | Recruiting |
| Memorial Sloan Kettering Westchester (Limited Protocol Activities) | Harrison | New York | 10604 | Recruiting |
| Memorial Sloan Kettering Cancer Center (All protocol activites) | New York | New York | 10065 | Recruiting |
| Memorial Sloan Kettering Nassau (Limited protocol activities) | Rockville Centre | New York | 11553 | Recruiting |
| Cincinnati Children's Hospital Medical Center (Data collection only) | Cincinnati | Ohio | 45229 | Recruiting |
| Cook Children's Health Care System (Data Collection Only) | Fort Worth | Texas | 76104 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05985161, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 5, 2026 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05985161 live on ClinicalTrials.gov.