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Recruiting Phase 2 Interventional

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

ClinicalTrials.gov ID: NCT05986292

Public ClinicalTrials.gov record NCT05986292. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 22, 2026, 8:29 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Master Protocol for Randomized, Placebo-Controlled, Phase 2 Clinical Trials of Multiple Interventions for the Treatment of Chronic Pain

Study identification

NCT ID
NCT05986292
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
10,000 participants

Conditions and interventions

Interventions

  • LY3016859 ISA Drug
  • LY3526318 ISA Drug
  • LY3556050 ISA Drug
  • LY3857210 ISA Drug
  • Placebo Drug
  • Placebo Oral Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 29, 2020
Primary completion
Mar 31, 2027
Completion
Mar 31, 2027
Last update posted
Apr 19, 2026

2020 – 2027

United States locations

U.S. sites
62
U.S. states
24
U.S. cities
55
Facility City State ZIP Site status
Central Research Associates Birmingham Alabama 35205 Recruiting
Simon Williamson Clinic Birmingham Alabama 35211 Completed
Synexus Clinical Research - Glendale Glendale Arizona 85306 Completed
Synexus Clinical Research US, Inc. Phoenix Arizona 85020 Recruiting
Arizona Research Center Phoenix Arizona 85053 Recruiting
Alliance for Multispecialty Research, LLC Tempe Arizona 85281 Completed
Irvine Clinical Research Irvine California 92614 Completed
Desert Oasis Healthcare Medical Group Palm Springs California 92262 Recruiting
Artemis Institute for Clinical Research Riverside California 92503 Recruiting
Artemis Institute for Clinical Research San Diego California 92123 Recruiting
CMR of Greater New Haven Hamden Connecticut 06517 Recruiting
VIN-Julie Schwartzbard Aventura Florida 33180 Completed
Bradenton Research Center, Inc. Bradenton Florida 34205 Recruiting
Clinical Research of South Florida Coral Gables Florida 33134 Not yet recruiting
Accel Research Sites - DeLand Clinical Research Unit DeLand Florida 32720 Recruiting
K2 MEDICAL Research THE VILLAGES Lady Lake Florida 32159 Recruiting
K2 Medical Research ORLANDO Maitland Florida 32751 Recruiting
Merritt Island Medical Research, LLC Merritt Island Florida 32952 Recruiting
Flourish Research - Miami, LLC Miami Florida 33135 Recruiting
University of Miami Don Suffer Clinical Research Building Miami Florida 33136 Not yet recruiting
New Horizon Research Center Miami Florida 33165 Recruiting
Suncoast Clinical Research, Inc. New Port Richey Florida 34652 Recruiting
Renstar Medical Research Ocala Florida 34470 Recruiting
Synexus Clinical Research US, Inc. Orlando Florida 32806 Not yet recruiting
Synexus Clinical Research - St. Petersburg Pinellas Park Florida 33781 Completed
Martin E. Hale M.D., P.A. Plantation Florida 33317 Completed
Precision Clinical Research Sunrise Florida 33351 Recruiting
Charter Research - Lady Lake The Villages Florida 32162 Recruiting
Synexus Clinical Research US, Inc. The Villages Florida 32162 Completed
Conquest Research Winter Park Florida 32789 Recruiting
North Georgia Clinical Research Woodstock Georgia 30189 Recruiting
Rocky Mountain Clinical Research Idaho Falls Idaho 83404 Not yet recruiting
Synexus Clinical Research Chicago Illinois 60602 Completed
Northwestern University Chicago Illinois 60611 Recruiting
Cotton O'Neil Clinical Research Center - Central Office Topeka Kansas 66606 Completed
DelRicht Research New Orleans Louisiana 70115 Recruiting
Boston Clinical Trials Boston Massachusetts 02131 Not yet recruiting
ActivMed Practices and Research Methuen Massachusetts 01844 Completed
Lucida Clinical Trials New Bedford Massachusetts 02740 Recruiting
MedVadis Research Corporation Waltham Massachusetts 02451 Recruiting
Great Lakes Research Group, Inc. Bay City Michigan 48706 Recruiting
StudyMetrix Research City of Saint Peters Missouri 63303 Recruiting
Clinvest Research LLC Springfield Missouri 65807 Recruiting
Synexus Clinical Research US, Inc. Omaha Nebraska 68144 Completed
Rochester Clinical Research, LLC Rochester New York 14609 Recruiting
PharmQuest Greensboro North Carolina 27408 Completed
Lillestol Research Fargo North Dakota 58104 Recruiting
Synexus - Cincinnati Cincinnati Ohio 45236 Completed
Aventiv Research Inc Columbus Ohio 43213 Completed
META Medical Research Institute Dayton Ohio 45432 Recruiting
DelRicht Research Tulsa Oklahoma 74133 Recruiting
Altoona Center For Clinical Research Duncansville Pennsylvania 16635 Recruiting
Clinical Research Center of Reading,LLC Wyomissing Pennsylvania 19610 Completed
Coastal Carolina Research Center North Charleston South Carolina 29405 Completed
FutureSearch Trials of Neurology Austin Texas 78731 Recruiting
Synexus Dallas Texas 75234 Completed
Cedar Health Research Dallas Texas 75251 Completed
Re:Cognition Health - Fort Worth Fort Worth Texas 76104 Recruiting
Synexus Clinical Research US, Inc. San Antonio Texas 78229 Completed
SYNEXUS Murray Utah 84123 Completed
Northwest Clinical Research Center Bellevue Washington 98007 Recruiting
Rainier Clinical Research Center Renton Washington 98057 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05986292, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 19, 2026 · Synced Apr 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05986292 live on ClinicalTrials.gov.

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