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Recruiting Not applicable Interventional

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

ClinicalTrials.gov ID: NCT05991453

Public ClinicalTrials.gov record NCT05991453. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 5, 2026, 6:31 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The investigators will conduct a 13,000-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries

Study identification

NCT ID
NCT05991453
Recruitment status
Recruiting
Study type
Interventional
Phase
Not applicable
Enrollment
13,000 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 12, 2023
Primary completion
Jul 30, 2027
Completion
Jul 30, 2028
Last update posted
Sep 3, 2026

2023 – 2028

United States locations

U.S. sites
24
U.S. states
16
U.S. cities
21
Facility City State ZIP Site status
University of Arkansas for Medical Sciences (UAMS) Little Rock Arkansas 72205 Recruiting
University of California San Francisco San Francisco California 94143 Recruiting
Stanford University Stanford California 94305 Not yet recruiting
Yale School of Medicine New Haven Connecticut 06510 Recruiting
Johns Hopkins School of Medicine Baltimore Maryland 21205 Recruiting
Massachusetts General Hospital Boston Massachusetts 02114 Recruiting
Brigham & Women's Boston Massachusetts 02115 Recruiting
University of Michigan Ann Arbor Michigan 48109 Recruiting
Henry Ford Health Detroit Michigan 48202 Recruiting
Washington University School of Medicine St Louis Missouri 63110 Recruiting
Dartmouth Hitchcock Medical Center Lebanon New Hampshire 03756 Recruiting
NYU Langone New York New York 10012 Recruiting
Weill Cornell Medicine New York New York 10065 Recruiting
University of North Carolina School of Medicine Chapel Hill North Carolina 27599 Recruiting
Duke University Durham North Carolina 27708 Recruiting
Wake Forest Winston-Salem North Carolina 27109 Recruiting
Oregon Health and Sciences University Portland Oregon 97239 Recruiting
University of Pennsylvania Philadelphia Pennsylvania 19104 Not yet recruiting
Temple University Philadelphia Pennsylvania 19140 Recruiting
University of Texas Southwestern Dallas Texas 75390 Recruiting
University of Texas - MD Anderson Houston Texas 77030 Recruiting
University of Utah - Medical Salt Lake City Utah 84132 Recruiting
UVA Health Charlottesville Virginia 22908 Recruiting
University of Washington Seattle Washington 98195 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05991453, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 3, 2026 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05991453 live on ClinicalTrials.gov.

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