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Recruiting Phase 3 Interventional

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

ClinicalTrials.gov ID: NCT06012240

Public ClinicalTrials.gov record NCT06012240. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 29, 2026, 8:39 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Randomized, Placebo-controlled, Double-blind Program to Evaluate Efficacy and Safety of Upadacitinib in Adult and Adolescent Subjects With Severe Alopecia Areata

Study identification

NCT ID
NCT06012240
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
AbbVie
Industry
Enrollment
1,500 participants

Conditions and interventions

Interventions

  • Placebo Drug
  • Upadacitinib Drug

Drug

Eligibility (public fields only)

Age range
12 Years to 63 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 10, 2023
Primary completion
Mar 31, 2030
Completion
Mar 31, 2030
Last update posted
Apr 16, 2026

2023 – 2030

United States locations

U.S. sites
74
U.S. states
26
U.S. cities
62
Facility City State ZIP Site status
Total Skin and Beauty Dermatology Center /ID# 259539 Birmingham Alabama 35205 Active, not recruiting
Duplicate_Advanced Research Associates - Glendale /ID# 259108 Glendale Arizona 85308 Completed
Southwest Skin Specialists /ID# 258234 Phoenix Arizona 85018-3953 Completed
Alliance Dermatology and Mohs Center /ID# 258111 Phoenix Arizona 85032 Active, not recruiting
Johnson Dermatology Clinic /ID# 259103 Fort Smith Arkansas 72916-6103 Active, not recruiting
Duplicate_JOSEPH RAOOF MD,INC /ID# 258031 Encino California 91436 Completed
First OC Dermatology /ID# 259220 Fountain Valley California 92708 Recruiting
University of California Irvine /ID# 259096 Irvine California 92697-1385 Active, not recruiting
Dermatology Research Associates /ID# 258033 Los Angeles California 90045 Recruiting
Stanford University School of Medicine - Redwood City /ID# 259542 Redwood City California 94063 Completed
Integrative Skin Science and Research /ID# 258114 Sacramento California 95815 Recruiting
University of California Davis Health /ID# 258112 Sacramento California 95817 Recruiting
Clinical Trials Research Institute /ID# 258021 Thousand Oaks California 91320-2130 Recruiting
Skin Care Research Boca Raton /ID# 258012 Boca Raton Florida 33486-2269 Recruiting
Apex Clinical Trials /ID# 259205 Brandon Florida 33511 Active, not recruiting
Florida Academic Dermatology Center /ID# 259353 Coral Gables Florida 33134-5755 Active, not recruiting
Skin Research Institute LLC /ID# 259207 Coral Gables Florida 33146-1837 Completed
Revival Research /ID# 259213 Doral Florida 33122-1902 Completed
Skin Care Research - Hollywood /ID# 259210 Hollywood Florida 33021-6748 Recruiting
GSI Clinical Research, LLC /ID# 259352 Margate Florida 33063 Recruiting
Life Clinical Trials /ID# 259358 Margate Florida 33063 Active, not recruiting
Lenus Research and Medical Group /ID# 259356 Miami Florida 33172 Recruiting
International Clinical Research - Sanford /ID# 259547 Sanford Florida 32771 Completed
FWD Clinical Research /ID# 266687 Tamarac Florida 33321-2931 Completed
Advanced Clinical Research Institute /ID# 259204 Tampa Florida 33607 Recruiting
Avita Clinical Research /ID# 258011 Tampa Florida 33613-1825 Completed
Cleaver Medical Group Dermatology /ID# 259801 Dawsonville Georgia 30534 Active, not recruiting
Marietta Dermatology /ID# 259818 Marietta Georgia 30060 Active, not recruiting
Northwestern University Feinberg School of Medicine /ID# 259555 Chicago Illinois 60611-2927 Completed
NorthShore University HealthSystem - Skokie /ID# 266684 Skokie Illinois 60077 Active, not recruiting
Indiana University Health University Hospital /ID# 259827 Indianapolis Indiana 46202 Recruiting
U.S. Dermatology Partners Leawood /ID# 259203 Leawood Kansas 66211-1453 Completed
Tulane University School of Medicine /ID# 259799 New Orleans Louisiana 70112 Recruiting
Raven Clinical Research /ID# 268453 Marriottsville Maryland 21104 Active, not recruiting
MetroBoston Clinical Partners /ID# 259559 Boston Massachusetts 02135-3511 Active, not recruiting
Lahey Hospital & Medical Center /ID# 260484 Burlington Massachusetts 01805 Completed
Great Lakes Research Group - Bay City /ID# 259100 Bay City Michigan 48706 Completed
Hamzavi Dermatology - Canton /ID# 260115 Canton Michigan 48187 Completed
Clin Res Inst of Michigan, LLC /ID# 259802 Chesterfield Michigan 48047 Active, not recruiting
Clarkston Dermatology /ID# 258018 Clarkston Michigan 48346 Recruiting
Henry Ford Medical Center - New Center One /ID# 258067 Detroit Michigan 48202-3046 Active, not recruiting
M Health Fairview University of Minnesota Medical Center - East Bank /ID# 260122 Minneapolis Minnesota 55455 Active, not recruiting
Minnesota Clinical Study Center /ID# 259218 New Brighton Minnesota 55112 Completed
Dermatology and Skin Center of Lees Summit /ID# 259206 Lee's Summit Missouri 64064-2301 Completed
Physician Research Collaboration, LLC /ID# 259354 Lincoln Nebraska 68516 Active, not recruiting
Skin Specialists /ID# 259237 Omaha Nebraska 68144 Recruiting
Skin Cancer and Dermatology Institute - Reno /ID# 259208 Reno Nevada 89509 Recruiting
The Skin Center Dermatology Group /ID# 266748 New City New York 10956-7153 Active, not recruiting
Schweiger Dermatology, P.C. /ID# 258007 New York New York 07044-2946 Completed
Schweiger Dermatology, P.C. /ID# 259531 New York New York 07044-2946 Completed
Equity Medical, LLC /ID# 266680 New York New York 10023-7340 Recruiting
Icahn School of Medicine at Mount Sinai /ID# 259808 New York New York 10029 Active, not recruiting
Sadick Research Group LLC /ID# 266790 New York New York 10075 Recruiting
Piedmont Plastic Surgery and Dermatology /ID# 258206 Huntersville North Carolina 28078-7961 Completed
Cleveland Clinic - Cleveland /ID# 258113 Cleveland Ohio 44195 Recruiting
Remington-Davis Clinical Research /ID# 258106 Columbus Ohio 43215 Active, not recruiting
Dermatologists of Southwest Ohio, Inc /ID# 260116 Mason Ohio 45040-4520 Recruiting
Dermatologist of Central States (DOCS) Clinical Research - Springfield /ID# 266746 Springfield Ohio 45505 Completed
Oregon Dermatology and Research Center /ID# 258243 Portland Oregon 97210 Recruiting
Oregon Medical Research Center /ID# 258107 Portland Oregon 97223 Active, not recruiting
University of Pittsburgh Medical Center /ID# 266681 Pittsburgh Pennsylvania 15213 Active, not recruiting
Medical University of South Carolina /ID# 259828 Charleston South Carolina 29425 Active, not recruiting
ADCS - Spartanburg /ID# 278359 Spartanburg South Carolina 29307 Recruiting
Health Concepts /ID# 266678 Rapid City South Dakota 57702 Active, not recruiting
International Clinical Research - Tennessee LLC /ID# 259552 Murfreesboro Tennessee 37130-2450 Recruiting
Arlington Research Center, Inc /ID# 258028 Arlington Texas 76011 Recruiting
Bellaire Dermatology Associates /ID# 259360 Bellaire Texas 77401 Recruiting
U.S. Dermatology Partners - Cedar Park /ID# 259367 Cedar Park Texas 78613 Recruiting
Dermatology Treatment and Research Center /ID# 259357 Dallas Texas 75230 Recruiting
Modern Research Associates, PLLC /ID# 259349 Dallas Texas 75231 Active, not recruiting
Reveal Research Institute - Dallas /ID# 259361 Dallas Texas 75235 Completed
Center for Clinical Studies - Houston - Northwest Freeway /ID# 258036 Houston Texas 77065 Active, not recruiting
Progressive Clinical Research /ID# 259365 San Antonio Texas 78229 Active, not recruiting
Complete Dermatology /ID# 258025 Sugar Land Texas 77479-3794 Active, not recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 194 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06012240, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 16, 2026 · Synced Apr 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06012240 live on ClinicalTrials.gov.

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