Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction
Public ClinicalTrials.gov record NCT06017609. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy, Safety and Tolerability of JTT-861 Administered for 12 Weeks in Subjects With Heart Failure With Reduced Ejection Fraction
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy, safety, tolerability and pharmacokinetics of JTT-861 administered once daily for 12 weeks in subjects with heart failure with reduced ejection fraction (HFrEF) who are on a stable, guideline-directed medical therapy for heart failure.
Study identification
- NCT ID
- NCT06017609
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 314 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 30 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 20, 2023 (Actual)
- Primary completion
- May 18, 2026 (Actual)
- Completion
- May 18, 2026 (Actual)
- Last update posted
- Sep 24, 2026
2023 – 2026
United States locations
- U.S. sites
- 20
- U.S. states
- 11
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arensia Exploratory Medicine Inc. | Phoenix | Arizona | 85015 | — |
| Nature Coast Clinical Research | Crystal River | Florida | 34429 | — |
| Indago Research & Health Center, Inc. | Hialeah | Florida | 33012 | — |
| Med Research of Florida | Miami | Florida | 33186 | — |
| Pharma Medical Innovation, Inc. | Miami Lakes | Florida | 33014 | — |
| Floridian Clinical Research | Miami Lakes | Florida | 33016 | — |
| Affinity Health | Park Ridge | Illinois | 60068 | — |
| ASHA Clinical Research-Munster, LLC | Hammond | Indiana | 46324 | — |
| Monroe Research, LLC | West Monroe | Louisiana | 71291 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Profound Research LLC | Farmington Hills | Michigan | 48334 | — |
| NextStage Clinical Research - (Kansas City [01]) | Kansas City | Missouri | 64114 | — |
| Laurelton Heart Specialist P.C. | Rosedale | New York | 11422 | — |
| Capital Area Research, LLC | Camp Hill | Pennsylvania | 17011 | — |
| Onsite Clinical Solutions, LLC | Rock Hill | South Carolina | 29732 | — |
| NextStage Clinical Research-Beaumont- (01) | Beaumont | Texas | 77702 | — |
| Cypress Heart and Vascular Center | Cypress | Texas | 77429 | — |
| NextStage Clinical Research-Port Arthur-(02) | Port Arthur | Texas | 77642 | — |
| Sherman Clinical Research | Sherman | Texas | 75092 | — |
| Waco Cardiology Associates - NextStage Clinical Research | Waco | Texas | 76712 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 55 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06017609, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 24, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06017609 live on ClinicalTrials.gov.